http://hdl.handle.net/10366/3971 2026-04-22T07:53:01Z 2026-04-22T07:53:01Z Hijazi Vega, Maruan Fillat, Cristina Medina Jiménez, José María Velasco Criado, Ana Purificación http://hdl.handle.net/10366/155279 2025-04-30T19:26:20Z 2012-01-01T00:00:00Z

[EN]Down syndrome (DS) is a genetic disease characterized by the presence of an extra copy of chromosome 21, resulting in a trisomy. The genetic origin was discovered in 1959 by Lejeune. Several defects in cortical lamination have been described during foetal development, that affect key brain regions involved in learning and memory processes.

2012-01-01T00:00:00Z