Compartir
Título
Using beta-lactam antibiotics in patients with a history of beta-lactam allergy: current concepts
Autor(es)
Materia
β-lactams
Diagnosis
Cross-reactivity
Hypersensitivity
Clasificación UNESCO
3207.01 Alergias
Fecha de publicación
2017
Editor
Polish Archives of Internal Medicine
Citación
Moreno, E., Laffond, E., Muñoz-Bellido, F. J., Gracia, M. T., Macías, E. M., & Dávila, I. (2017). Using β-lactam antibiotics in patients with a history of β-lactam allergy: current concepts. Polish Archives of Internal Medicine, 127(7), 540–549. https://doi.org/10.20452/pamw.4066
Resumen
[EN]β-lactams are the most widely used antibiotic family, but they are also the most common cause of drug-induced hypersensitivity reactions. The estimated prevalence of reported penicillin allergy ranges between 9% and 12%, although a high percentage of patients with a history of penicillin allergy have no subsequent reactions on reexposure to β-lactams. A self-reported penicillin allergy has been associated with antimicrobial resistance, increased cost, intensive care admission, and death, making it essential to establish an accurate diagnosis. In addition to a thorough clinical history, diagnostic methods include skin tests, in vitro tests, and drug-challenge tests. In this review, the diagnosis and management of patients with self-reported penicillin allergy is discussed, including the recently introduced antimicrobial stewardship strategy.
URI
ISSN
1897-9483
DOI
10.20452/pamw.4066
Versión del editor
Colecciones
Ficheros en el ítem
Tamaño:
194.9Kb
Formato:
Adobe PDF