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Título
Intracavity biosensor based on the Nd:YAG waveguide laser: tumor cells and dextrose solutions
Autor(es)
Materia
Laser materials
Laser materials processing
Q switched lasers
Solid state lasers
Ultrafast lasers
Waveguide lasers
Fecha de publicación
2017-12
Citación
Li, G., Li, H., Gong, R., Tan, Y., Vázquez de Aldana, J.R., Sun, Y. and Chen, F. (2017). Intracavity biosensor based on the Nd:YAG waveguide laser: tumor cells and dextrose solutions. Photon. Res. 5, 728-732 (2017)
Resumen
[EN]This work demonstrates the Nd:YAG waveguide laser as an efficient platform for the bio-sensing of dextrose solutions and tumor cells. The waveguide was fabricated in an Nd:YAG crystal with the cooperation of ultrafast laser writing and ion irradiation. The laser oscillation in the Nd:YAG waveguide is ultrasensitive to the external environment of the waveguide. Even a weak disturbance leads to a large variation of the output power of the laser. According to this feature, an Nd:YAG waveguide coated with graphene and WSe2 layers is used as substrate for the microfluidic channel. When the microflow crosses the Nd:YAG waveguide, the laser oscillation in the waveguide is disturbed and induces fluctuation of the output laser. According to the fluctuation, the microflow is detected with a sensitivity of 10 mW/RIU.
URI
DOI
10.1364/PRJ.5.000728
Versión del editor
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- ALF. Artículos [303]
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