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Título
Integrating Nextflow and AWS for Large-Scale Genomic Analysis: A Hypothetical Case Study
Autor(es)
Palabras clave
Next-Generation sequencing
Cloud computing
Distributed Computing
Clasificación UNESCO
1203.17 Informática
2409 Genética
Fecha de publicación
2022
Resumen
[EN]This article explores the innovative combination of Nextflow and Amazon Web Services (AWS) to address the challenges
inherent in large-scale genomic analysis. Focusing on a hypothetical case called "The Pacific Genome Atlas", it illustrates
how a research organization could approach the sequencing and analysis of 10,000 genomes. Although the "Pacific Genome
Atlas" is a fictional example used for illustrative purposes only, it highlights the real challenges associated with large
genomic projects, such as handling huge volumes of data and the need for intensive computational analysis. Through the
integration of Nextflow, a workflow management tool, with the AWS cloud infrastructure, we demonstrate how these
challenges can be overcome, offering scalable, flexible and cost-effective solutions for genomic research. The adoption of
modern technologies, such as those described in this article, is essential to advance the field of genomics and accelerate
scientific discoveries.
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