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Título
Is cognitive reserve associated with the prevention of cognitive decline after stroke? A Systematic review and meta-analysis.
Autor(es)
Materia
Cerebrovascular diseases
Cognitive disorders
Dementia
Reserve
Education
Fecha de publicación
2022-12-22
Editor
Elsevier
Citación
Contador, I., Alzola, P., Stern, Y., de la Torre-Luque, A., Bermejo-Pareja, F., & Fernández-Calvo, B. (2022). Is cognitive reserve associated with the prevention of cognitive decline after stroke? A Systematic review and meta-analysis. Ageing research reviews, 84, 101814. Advance online publication. https://doi.org/10.1016/j.arr.2022.101814
Resumen
[EN]Objective: To conduct a systematic review and meta-analyses of the effect of socio-behavioral cognitive reserve
(CR) proxies on cognitive decline after stroke.
Method: Three journal search and indexing databases (PubMed, Scopus and Web of Sciences) were crossed to
examine the scientific evidence systematically. In addition, meta-analytic techniques, using mixed-effect
methods, were carried out to estimate the impact (pooled effect size) of CR proxies on either dementia inci dence or cognitive decline after stroke.
Results: Twenty-two studies were included in the systematic revision, whereas nineteen of them were eligible for
the meta-analysis. The findings showed that high education is associated with a decreased rate of post-stroke
dementia. Moreover, other CR proxies (e.g., occupation, bilingualism or social interaction) demonstrate a pro tective effect against non-dementia cognitive decline after stroke, although some inconsistencies were found in
the literature. Regarding the meta-analysis, occupational attainment and education) showed a protective effect
against post-stroke cognitive impairment diagnosis in comparison with a mixed category of different CR proxies.
Second, a main cognitive change effect was found, pointing to greater cognitive change after stroke in those with
low vs. high CR.
Conclusions: Our findings emphasize that CR may prevent cognitive decline after stroke, but this effect can be
modulated by different factors such the CR proxy and individual characteristics such as age or type of lesion. The
methodological divergences of the studies (i.e., follow-up intervals, cognitive outcomes) need unification to
diminish external sources of variability for predicting rates of cognitive decline after stroke.
URI
ISSN
1568-1637
DOI
10.1016/j.arr.2022.101814
Colecciones
- GECYS. Artículos [16]
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