A translational systems biology approach in both animals and humans identifies a functionally related module of accumbal genes involved in the regulation of reward processing and binge drinking in males

Stacey, David; Lourdusamy, Anbarasu; Ruggeri, Barbara; Maroteaux, Matthieu; Jia, Tianye; Cattrell, Anna; Nymberg, Charlotte; Banaschewski, Tobias; Bhattacharyya, Sohinee; Band, Hamid; Barker, Gareth; Bokde, Arun; Büchel, Christian; Carvalho, Fabiana; Conrod, Patricia; Desrivières, Sylvane; Easton, Alanna C.; Fauth-Buehler, Mira; Fernández Medarde, Alberto; Flor, Herta; Frouin, Vincent; Gallinat, Jurgen; Garavanh, Hugh; Heinz, Andreas; Ittermann, Bernd; Lathrop, Mark; Lawrence, Claire; Loth, Eva; Mann, Karl; Martinot, Jean-Luc; Nees, Frauke; Paus, Tomas; Pausova, Zdenka; Rietschel, Marcella; Rotter, Andrea; Santos de Dios, Eugenio Miguel; Smolka, Michael; Sommer, Wolfgang; Mameli, Manuel; Spanagel, Rainer; Girault, Jean-Antoine; Mueller, Christian; Schumann, Gunter

doi:10.1503/jpn.150138

Título

A translational systems biology approach in both animals and humans identifies a functionally related module of accumbal genes involved in the regulation of reward processing and binge drinking in males

dc.contributor.author	Stacey, David
dc.contributor.author	Lourdusamy, Anbarasu
dc.contributor.author	Ruggeri, Barbara
dc.contributor.author	Maroteaux, Matthieu
dc.contributor.author	Jia, Tianye
dc.contributor.author	Cattrell, Anna
dc.contributor.author	Nymberg, Charlotte
dc.contributor.author	Banaschewski, Tobias
dc.contributor.author	Bhattacharyya, Sohinee
dc.contributor.author	Band, Hamid
dc.contributor.author	Barker, Gareth
dc.contributor.author	Bokde, Arun
dc.contributor.author	Büchel, Christian
dc.contributor.author	Carvalho, Fabiana
dc.contributor.author	Conrod, Patricia
dc.contributor.author	Desrivières, Sylvane
dc.contributor.author	Easton, Alanna C.
dc.contributor.author	Fauth-Buehler, Mira
dc.contributor.author	Fernández Medarde, Alberto
dc.contributor.author	Flor, Herta
dc.contributor.author	Frouin, Vincent
dc.contributor.author	Gallinat, Jurgen
dc.contributor.author	Garavanh, Hugh
dc.contributor.author	Heinz, Andreas
dc.contributor.author	Ittermann, Bernd
dc.contributor.author	Lathrop, Mark
dc.contributor.author	Lawrence, Claire
dc.contributor.author	Loth, Eva
dc.contributor.author	Mann, Karl
dc.contributor.author	Martinot, Jean-Luc
dc.contributor.author	Nees, Frauke
dc.contributor.author	Paus, Tomas
dc.contributor.author	Pausova, Zdenka
dc.contributor.author	Rietschel, Marcella
dc.contributor.author	Rotter, Andrea
dc.contributor.author	Santos de Dios, Eugenio Miguel
dc.contributor.author	Smolka, Michael
dc.contributor.author	Sommer, Wolfgang
dc.contributor.author	Mameli, Manuel
dc.contributor.author	Spanagel, Rainer
dc.contributor.author	Girault, Jean-Antoine
dc.contributor.author	Mueller, Christian
dc.contributor.author	Schumann, Gunter
dc.date.accessioned	2024-03-11T09:15:19Z
dc.date.available	2024-03-11T09:15:19Z
dc.date.issued	2016
dc.identifier.citation	Stacey, D., Lourdusamy, A., Ruggeri, B., Maroteaux, M., Jia, T., Cattrell, A., ... & Schumann, G. (2016). A translational systems biology approach in both animals and humans identifies a functionally related module of accumbal genes involved in the regulation of reward processing and binge drinking in males. Journal of Psychiatry and Neuroscience, 41(3), 192-202. https://doi.org/10.1503/jpn.150138	es_ES
dc.identifier.issn	1180-4882
dc.identifier.uri	http://hdl.handle.net/10366/156471
dc.description.abstract	[ES]Nuestros hallazgos indican que el módulo accumbal M5, inicialmente identificado como desregulado en ratones macho Rasgrf2–/–, también es relevante para los fenotipos humanos relacionados con el alcohol, potencialmente a través de la modulación de los mecanismos de refuerzo en el NAcc. Por lo tanto, proponemos que los genes que comprenden este módulo representan candidatos importantes para una mayor aclaración en el contexto de los fenotipos relacionados con el alcohol.	es_ES
dc.description.sponsorship	MINECO PS09/01979 y RD06/0020/0000	es_ES
dc.language.iso	eng	es_ES
dc.publisher	Canadian Medical Association	es_ES
dc.subject	Rasgrf2	es_ES
dc.subject	Mesolimbic dopamine system	es_ES
dc.subject	Dopaminergic neurons	es_ES
dc.subject	Binge drinking	es_ES
dc.subject.mesh	Alcoholism	*
dc.title	A translational systems biology approach in both animals and humans identifies a functionally related module of accumbal genes involved in the regulation of reward processing and binge drinking in males	es_ES
dc.type	info:eu-repo/semantics/article	es_ES
dc.relation.publishversion	https://doi.org/10.1503/jpn.150138	es_ES
dc.identifier.doi	10.1503/jpn.150138
dc.relation.projectID	PS09/01979	es_ES
dc.rights.accessRights	info:eu-repo/semantics/openAccess	es_ES
dc.identifier.essn	1488-2434
dc.journal.title	Journal of Psychiatry and Neuroscience	es_ES
dc.volume.number	41	es_ES
dc.issue.number	3	es_ES
dc.page.initial	192	es_ES
dc.page.final	202	es_ES
dc.type.hasVersion	info:eu-repo/semantics/publishedVersion	es_ES
dc.subject.decs	alcoholismo	*

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