Título
Association between mutation of the NF2gene and monosomy 22 in menopausal women with sporadic meningiomas
Autor(es)
Palabras clave
Mutation
NF2 gene
Sporadic meningiomas
Monosomy 22
Menopausal women
Clasificación UNESCO
Fecha de publicación
2013
Editor
BioMed Central
Citación
Tabernero, M., Jara-Acevedo, M., Nieto, A. B., Caballero, A. R., Otero, Á., Sousa, P., Gonçalves, J., Domingues, P. H., & Orfao, A. (2013). Association between mutation of the NF2 gene and monosomy 22 in menopausal women with sporadic meningiomas. BMC Medical Genetics, 14(1). https://doi.org/10.1186/1471-2350-14-114
Resumen
[EN] Meningioma was the first solid tumor shown to contain a recurrent genetic alteration e.g. monosomy 22/del(22q), NF2 being the most relevant gene involved. Although monosomy 22/del(22q) is present in half of all meningiomas, and meningiomas frequently carry NF2 mutations, no study has been reported so far in which both alterations are simultaneously assessed and correlated with the features of the disease.
URI
ISSN
1471-2350
DOI
Versión del editor
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