Ver item 

Mostrar registro simples

Título
Pharmacogenetics and the Treatment of Asthma
dc.contributor.authorIsidoro García, María 
dc.contributor.authorSánchez Martín, Almudena
dc.contributor.authorGarcía Sánchez, María Asunción 
dc.contributor.authorSanz Lozano, Catalina Sofía 
dc.contributor.authorGarcía-Berrocal, Belén
dc.contributor.authorDávila González, Ignacio Jesús 
dc.date.accessioned2024-07-09T08:31:21Z
dc.date.available2024-07-09T08:31:21Z
dc.date.issued2017-08
dc.identifier.citationIsidoro-García M, Sánchez-Martín A, García-Sánchez A, Sanz C, García-Berrocal B, Dávila I. Pharmacogenetics and the treatment of asthma. Pharmacogenomics. 2017 Aug;18(13):1271-1280. doi: 10.2217/pgs-2017-0024. Epub 2017 Aug 4. PMID: 28776467.es_ES
dc.identifier.issn1462-2416
dc.identifier.urihttp://hdl.handle.net/10366/158861
dc.description.abstract[EN] Heterogeneity defines both the natural history of asthma as well as patient's response to treatment. Pharmacogenomics contribute to understand the genetic basis of drug response and thus to define new therapeutic targets or molecular biomarkers to evaluate treatment effectiveness. This review is initially focused on different genes so far involved in the pharmacological response to asthma treatment. Specific considerations regarding allergic asthma, the pharmacogenetics aspects of polypharmacy and the application of pharmacogenomics in new drugs in asthma will also be addressed. Finally, future perspectives related to epigenetic regulatory elements and the potential impact of systems biology in pharmacogenetics of asthma will be considered.es_ES
dc.language.isoenges_ES
dc.publisherTaylor & Francises_ES
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectAllergyes_ES
dc.subjectAsthmaes_ES
dc.subjectPersonalized medicinees_ES
dc.subjectPharmacogenomicses_ES
dc.subjectPhenotypeses_ES
dc.subject.meshGenetics *
dc.subject.meshAllergy and Immunology *
dc.titlePharmacogenetics and the Treatment of Asthmaes_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.relation.publishversionhttps://doi.org/10.2217/pgs-2017-0024es_ES
dc.subject.unesco3207.01 Alergiases_ES
dc.subject.unesco2409 Genéticaes_ES
dc.identifier.doi10.2217/pgs-2017-0024
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses_ES
dc.identifier.pmid28776467
dc.identifier.essn1744-8042
dc.journal.titlePharmacogenomicses_ES
dc.volume.number18es_ES
dc.issue.number13es_ES
dc.page.initial1271es_ES
dc.page.final1280es_ES
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersiones_ES
dc.subject.decsalergia e inmunología *
dc.subject.decsgenética *


Arquivos deste item

Thumbnail
Nome:
2017_DMG_IsidoroM_Pharmacogeno ...
Tamanho:
276.8Kb
Formato:
PDF
Descrição:
Artículo principal
Visualizar/Abrir

Este item aparece na(s) seguinte(s) coleção(s)

Mostrar registro simples

Attribution-NonCommercial-NoDerivatives 4.0 Internacional
Exceto quando indicado o contrário, a licença deste item é descrito como Attribution-NonCommercial-NoDerivatives 4.0 Internacional