Genomics and proteomics approaches for biomarker discovery in sporadic colorectal cancer with metastasis.

González González, María; García García, Jacinto; Alcázar Montero, José Antonio; González Fernández, Luis Miguel; Bengoechea Miranda, Oscar; Blanco Muñez, Óscar Javier; Orfao de Matos Correia e Vale, José Alberto; Sayagués Manzano, José María; Fuentes, Manuel

Título

Genomics and proteomics approaches for biomarker discovery in sporadic colorectal cancer with metastasis.

Autor(es)

González González, María

García García, Jacinto

Alcázar Montero, José Antonio

González Fernández, Luis Miguel

Bengoechea Miranda, Oscar

Blanco Muñez, Óscar Javier

Orfao de Matos Correia e Vale, José Alberto

Sayagués Manzano, José María

Fuentes, Manuel

Palabras clave

Sporadic colorectal carcinoma

Metastases

Genomic biomarker

Proteomic biomarkers

Clasificación UNESCO

3207.13 Oncología

3213 Cirugía

Fecha de publicación

2013

Citación

González-González, M., Garcia, J. G., Montero, J. A., Fernandez, L. M., Bengoechea, O., Muñez, O. B., Orfao, A., Sayagues, J. M., & Fuentes, M. (2013). Genomics and proteomics approaches for biomarker discovery in sporadic colorectal cancer with metastasis. Cancer genomics & proteomics, 10(1), 19–25.

Resumen

Sporadic colorectal cancer (sCRC) is one of the most frequent types of cancer in Europe. Despite understanding of its tumorigenesis, the metastatic process is not yet clear. In this article, we review the most significant genetic and proteomic advances that have been made in regards to research of the sCRC metastatic process, and the new biomarkers that are able to predict disease prognosis or response to treatments, in order to define personalized medicine.

URI

https://hdl.handle.net/10366/160738

Versión del editor

https://cgp.iiarjournals.org/content/10/1/19.long

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