Título
Identification of a characteristic copy number alteration profile by high‐resolution single nucleotide polymorphism arrays associated with metastatic sporadic colorectal cancer
Autor(es)
Palabras clave
Colorectal carcinoma
Copy number change
Liver metastases
Single nucleotide
Polymorphism array
Clasificación UNESCO
Fecha de publicación
2014
Editor
Wiley
Citación
González‐González, M., Fontanillo, C., Abad, M. M., Gutiérrez, M. L., Mota, I., Bengoechea, O., Santos‐Briz, Á., Blanco, O., Fonseca, E., Ciudad, J., Fuentes, M., De Las Rivas, J., Alcazar, J. A., García, J., Muñoz‐Bellvis, L., Orfao, A., y Sayagués, J. M. (2014). Identification of a characteristic copy number alteration profile by high‐resolution single nucleotide polymorphism arrays associated with metastatic sporadic colorectal cancer. Cancer, 120(13), 1948-1959. https://doi.org/10.1002/cncr.28681
Resumen
[EN]Metastatic dissemination is the most frequent cause of death in patients with sporadic colorectal cancer (sCRC). It is believed that the metastatic process is related at least in part to a specific background of genetic alterations accumulated in cells from primary tumors, and the ability to detect such alterations is critical for the identification of patients with sCRC who are at risk of developing metastases.
URI
ISSN
0008-543X
DOI
Versión del editor
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