Use of noninvasive ventilation on internal wards for elderly patients with limitations to respiratory care: a cohort study

Abstract

[EN]Background The use of noninvasive positive pressure ventilation (NPPV) outside the intensive wards has beenevaluated in patients with no limitation on life-sustaining support. Our aim was to evaluate its usefulness ingeneral wards for patients with NPPV as the ceiling of ventilator care when admission to the intensive care unit(ICU) has been withheld.Materials and methods Noninvasive positive pressure ventilation was used in 44 patients with acuterespiratory failure (ARF) and limitations to respiratory care– 22 with chronic obstructive pulmonary disease(COPD) exacerbations and 22 with acute cardiogenic pulmonary oedema (CPE). Survival at hospital discharge,and survival and readmission rate at 12 months were assessed.Results Sixty-three per cent of COPD and 55% of CPE patients survived hospital discharge; and 50% and 37%respectively, were alive after 1 year. The cause of the in-hospital mortality was related to the admission diagno-sis in 88% of cases. Cancer in COPD patients [P = 0Æ040, odds ratio (OR) = 15, 95% CI = 1Æ14–198] and thecompletion of NPPV treatment in both diseases (P = 0Æ008, OR = 0Æ03, 95% CI = 0Æ00–0Æ39 for COPD andP = 0Æ010, OR = 0Æ04, 95% CI = 0Æ00–0Æ45 for CPE) were related to in-hospital mortality.Fifty-six per cent of COPD and 33% of CPE patients that survived hospital admission were readmitted.Conclusions Our study suggests that the use of NPPV in general wards could be a safe and effective option, asa last choice treatment, in patients with NPPV as the ceiling of ventilator care when admission to ICU has beenwithheld