Relationship of muscle mass determined by DEXA with spirometric results in healthy individuals

Abstract

[EN]Introduction: Muscle mass maybe a determining factor in the variability of spirometry results in indi-viduals of the same sex and age who have similar anthropometric characteristics. The aim of this studywas to determine the association between spirometric results from healthy individuals and their musclemass assessed by dual energy X-ray absorptiometry (DEXA).Methods: A sample of 161 women and 144 men, all healthy non-smokers, was studied. Ages rangedfrom18 to77 years. For each subject, spirometry results and total and regional lean mass values obtainedby full body DEXA were recorded. A descriptive analysis of the variables and a regression analysis wereperformed to study the relationship between spirometric variables and lean body mass, correcting forage and body mass index (BMI).Results: In both sexes all muscle mass variables correlated positively and significantly with spirometricvariables, and to a greater extent in men. After partial adjustment of correlations by age and BMI, thefactor which best explains the spirometric variables is the total lean body mass in men, and trunk leanbody mass in women.Conclusions: In men, muscle mass in the lower extremities is most closely associated with spirometricresults. In women, it is the muscle mass of the trunk. In both sexes muscle mass mainly affects FEV1.

[ES]Introducción: La cantidad de masa muscular podría ser un factor determinante que explicara la vari- abilidad de los resultados de la espirometría en individuos del mismo sexo y edad y de características antropométricas similares. El objetivo de este estudio es determinar si existe asociación entre los resulta- dos espirométricos de individuos sanos y su masa muscular estimada mediante absorciometría de rayos X (DEXA). Métodos: Se estudió una muestra de 161 mujeres y 143 varones sanos, no fumadores, de 18 a 77 a ˜nos. En cada sujeto se registraron los resultados de una espirometría y los valores de la masa magra total y regional obtenidos mediante DEXA. Se realizó un análisis descriptivo de las variables y un análisis de regresión para estudiar las relaciones entre variables espirométricas y masa magra, corrigiendo los efectos que pudieran ejercer la edad y el índice de masa corporal (IMC).