Título
Risks of organ preservation in rectal cancer: Data from two international registries on rectal cancer
Autor(es)
Palabras clave
Rectal cancer
Organ Preservation
Registries
Clasificación UNESCO
3207.13 Oncología
3213 Cirugía
Fecha de publicación
2025
Citación
Fernandez, L. M., São Julião, G. P., Santacruz, C. C., Renehan, A. G., Cano-Valderrama, O., Beets, G. L., Azevedo, J., Lorente, B. F., Rancaño, R. S., Biondo, S., Espin-Basany, E., Vailati, B. B., Nilsson, P. J., Martling, A., Van De Velde, C. J. H., Parvaiz, A., Habr-Gama, A., Perez, R. O., on behalf of the International Watch & Wait Database Consortium (IWWD) and the Spanish Rectal Cancer Viking Consortium (VIKINGO), … Zhang, Z. (2025). Risks of organ preservation in rectal cancer: Data from two international registries on rectal cancer. Journal of Clinical Oncology, 43(14), 1663-1672.
Resumen
[EN]Organ preservation has become an attractive alternative to surgery (total mesorectal excision [TME]) among patients with rectal cancer after neoadjuvant therapy who achieve a clinical complete response (cCR). Nearly 30% of these patients will develop local regrowth (LR). Although salvage resection is frequently feasible, there may be an increased risk for development of subsequent distant metastases (DM). The aim of this study is to compare the risk of DM between patients with LR after Watch and Wait (WW) and patients with near-complete pathologic response (nPCR) managed by TME at the time of reassessment of response.
URI
ISSN
0732-183X
DOI
Versión del editor
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