<?xml version="1.0" encoding="UTF-8"?><?xml-stylesheet type="text/xsl" href="static/style.xsl"?><OAI-PMH xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/ http://www.openarchives.org/OAI/2.0/OAI-PMH.xsd"><responseDate>2026-09-16T04:05:09Z</responseDate><request verb="GetRecord" identifier="oai:gredos.usal.es:10366/135288" metadataPrefix="mets">https://gredos.usal.es/oai/request</request><GetRecord><record><header><identifier>oai:gredos.usal.es:10366/135288</identifier><datestamp>2025-04-30T20:16:06Z</datestamp><setSpec>com_10366_135275</setSpec><setSpec>com_10366_4512</setSpec><setSpec>com_10366_3823</setSpec><setSpec>com_10366_4386</setSpec><setSpec>com_10366_4349</setSpec><setSpec>com_10366_3946</setSpec><setSpec>col_10366_135276</setSpec><setSpec>col_10366_4387</setSpec></header><metadata><mets xmlns="http://www.loc.gov/METS/" xmlns:doc="http://www.lyncode.com/xoai" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:xlink="http://www.w3.org/1999/xlink" xsi:schemaLocation="http://www.loc.gov/METS/ http://www.loc.gov/standards/mets/mets.xsd" PROFILE="DSpace METS SIP Profile 1.0" TYPE="DSpace ITEM" ID="&#xa;&#x9;&#x9;&#x9;&#x9;DSpace_ITEM_10366-135288" OBJID="&#xa;&#x9;&#x9;&#x9;&#x9;hdl:10366/135288">
<metsHdr CREATEDATE="2026-09-16T06:05:09Z">
<agent TYPE="ORGANIZATION" ROLE="CUSTODIAN">
<name>Gestión del Repositorio Documental de la Universidad de Salamanca</name>
</agent>
</metsHdr>
<dmdSec ID="DMD_10366_135288">
<mdWrap MDTYPE="MODS">
<xmlData xmlns:mods="http://www.loc.gov/mods/v3" xsi:schemaLocation="http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-1.xsd">
<mods:mods xsi:schemaLocation="http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-1.xsd">
<mods:name>
<mods:role>
<mods:roleTerm type="text">author</mods:roleTerm>
</mods:role>
<mods:namePart>Vega Cruz, Pastora Isabel</mods:namePart>
</mods:name>
<mods:name>
<mods:role>
<mods:roleTerm type="text">author</mods:roleTerm>
</mods:role>
<mods:namePart>Lamanna de Rocco, Rosalba</mods:namePart>
</mods:name>
<mods:name>
<mods:role>
<mods:roleTerm type="text">author</mods:roleTerm>
</mods:role>
<mods:namePart>Revollar Chávez, Silvana Roxani</mods:namePart>
</mods:name>
<mods:name>
<mods:role>
<mods:roleTerm type="text">author</mods:roleTerm>
</mods:role>
<mods:namePart>Francisco Sutil, Mario</mods:namePart>
</mods:name>
<mods:extension>
<mods:dateAccessioned encoding="iso8601">2017-09-21T10:56:41Z</mods:dateAccessioned>
</mods:extension>
<mods:extension>
<mods:dateAvailable encoding="iso8601">2017-09-21T10:56:41Z</mods:dateAvailable>
</mods:extension>
<mods:originInfo>
<mods:dateIssued encoding="iso8601">2014</mods:dateIssued>
</mods:originInfo>
<mods:identifier type="citation">Vega, P., Lamanna de R, R., Revollar, S. (2014). Integrated design and control of chemical processes : Part II: an illustrative example.Computers &amp; Chemical Engineering, 71, pp. 618-635.</mods:identifier>
<mods:identifier type="uri">http://hdl.handle.net/10366/135288</mods:identifier>
<mods:identifier type="doi">https://doi.org/10.1016/j.compchemeng.2014.09.019</mods:identifier>
<mods:abstract>[EN] In this paper, the integrated design paradigm is illustrated with several examples taken from the wide range of methodologies developed in last decades and presented in the first article of this series [Part 1]. The techniques included here belong to the category of simultaneous design and control in an optimization framework, and they have been developed by the authors’ research group and applied to the simultaneous process and control system design of the activated sludge process in a wastewater treatment plant (WWTP). In the present article, new aspects and results of those methodologies are presented for further understanding. The scope of the problem considers both a fixed plant layout and the plant structure selection by defining a simple superstructure. The control strategy chosen is a linear Model Predictive Controller (MPC) with terminal penalty in order to guarantee stability. As for the evaluation of the controllability, norm based indexes have been considered, and a multi-model approach to represent the uncertainty and assure robustness. The formulation of the optimization problem can be stated either as a multiobjective one considering costs and controllability, or as monoobjective adding some controllability constraints. Several strategies for solving the optimization problem are presented, mixing stochastic and deterministic methods, and genetic algorithms.</mods:abstract>
<mods:language>
<mods:languageTerm authority="rfc3066">eng</mods:languageTerm>
</mods:language>
<mods:accessCondition type="useAndReproduction"/>
<mods:subject>
<mods:topic>Integrated design</mods:topic>
</mods:subject>
<mods:subject>
<mods:topic>Controllability</mods:topic>
</mods:subject>
<mods:subject>
<mods:topic>Activated sludge process</mods:topic>
</mods:subject>
<mods:subject>
<mods:topic>Model predictive control, MPC</mods:topic>
</mods:subject>
<mods:subject>
<mods:topic>Terminal penalty</mods:topic>
</mods:subject>
<mods:subject>
<mods:topic>Wastewater treatment plant, WWTP</mods:topic>
</mods:subject>
<mods:subject>
<mods:topic>Controlabilidad</mods:topic>
</mods:subject>
<mods:subject>
<mods:topic>Tratamiento de lodos activados</mods:topic>
</mods:subject>
<mods:subject>
<mods:topic>Proceso de síntesis</mods:topic>
</mods:subject>
<mods:subject>
<mods:topic>Process synthesis</mods:topic>
</mods:subject>
<mods:subject>
<mods:topic>Chemical engineering</mods:topic>
</mods:subject>
<mods:titleInfo>
<mods:title>Integrated design and control of chemical processes : Part II: an illustrative example</mods:title>
</mods:titleInfo>
<mods:genre>info:eu-repo/semantics/article</mods:genre>
</mods:mods>
</xmlData>
</mdWrap>
</dmdSec>
<amdSec ID="TMD_10366_135288">
<rightsMD ID="RIG_10366_135288">
<mdWrap OTHERMDTYPE="DSpaceDepositLicense" MDTYPE="OTHER" MIMETYPE="text/plain">
<binData>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</binData>
</mdWrap>
</rightsMD>
</amdSec>
<amdSec ID="FO_10366_135288_1">
<techMD ID="TECH_O_10366_135288_1">
<mdWrap MDTYPE="PREMIS">
<xmlData xmlns:premis="http://www.loc.gov/standards/premis" xsi:schemaLocation="http://www.loc.gov/standards/premis http://www.loc.gov/standards/premis/PREMIS-v1-0.xsd">
<premis:premis>
<premis:object>
<premis:objectIdentifier>
<premis:objectIdentifierType>URL</premis:objectIdentifierType>
<premis:objectIdentifierValue>https://gredos.usal.es/bitstream/10366/135288/1/art5b_Vega%20Integrated%20design%20PART%20II_final.pdf</premis:objectIdentifierValue>
</premis:objectIdentifier>
<premis:objectCategory>File</premis:objectCategory>
<premis:objectCharacteristics>
<premis:fixity>
<premis:messageDigestAlgorithm>MD5</premis:messageDigestAlgorithm>
<premis:messageDigest>d7ad70b2996485d293593ab5c28e3769</premis:messageDigest>
</premis:fixity>
<premis:size>408417</premis:size>
<premis:format>
<premis:formatDesignation>
<premis:formatName>application/pdf</premis:formatName>
</premis:formatDesignation>
</premis:format>
</premis:objectCharacteristics>
<premis:originalName>art5b_Vega Integrated design PART II_final.pdf</premis:originalName>
</premis:object>
</premis:premis>
</xmlData>
</mdWrap>
</techMD>
</amdSec>
<amdSec ID="FT_10366_135288_7">
<techMD ID="TECH_T_10366_135288_7">
<mdWrap MDTYPE="PREMIS">
<xmlData xmlns:premis="http://www.loc.gov/standards/premis" xsi:schemaLocation="http://www.loc.gov/standards/premis http://www.loc.gov/standards/premis/PREMIS-v1-0.xsd">
<premis:premis>
<premis:object>
<premis:objectIdentifier>
<premis:objectIdentifierType>URL</premis:objectIdentifierType>
<premis:objectIdentifierValue>https://gredos.usal.es/bitstream/10366/135288/7/art5b_Vega%20Integrated%20design%20PART%20II_final.pdf.txt</premis:objectIdentifierValue>
</premis:objectIdentifier>
<premis:objectCategory>File</premis:objectCategory>
<premis:objectCharacteristics>
<premis:fixity>
<premis:messageDigestAlgorithm>MD5</premis:messageDigestAlgorithm>
<premis:messageDigest>8fd75324a95a64d52e2b4efc812e9bce</premis:messageDigest>
</premis:fixity>
<premis:size>72822</premis:size>
<premis:format>
<premis:formatDesignation>
<premis:formatName>text/plain</premis:formatName>
</premis:formatDesignation>
</premis:format>
</premis:objectCharacteristics>
<premis:originalName>art5b_Vega Integrated design PART II_final.pdf.txt</premis:originalName>
</premis:object>
</premis:premis>
</xmlData>
</mdWrap>
</techMD>
</amdSec>
<fileSec>
<fileGrp USE="ORIGINAL">
<file ID="BITSTREAM_ORIGINAL_10366_135288_1" MIMETYPE="application/pdf" SEQ="1" SIZE="408417" CHECKSUM="d7ad70b2996485d293593ab5c28e3769" CHECKSUMTYPE="MD5" ADMID="FO_10366_135288_1" GROUPID="GROUP_BITSTREAM_10366_135288_1">
<FLocat xlink:type="simple" LOCTYPE="URL" xlink:href="https://gredos.usal.es/bitstream/10366/135288/1/art5b_Vega%20Integrated%20design%20PART%20II_final.pdf"/>
</file>
</fileGrp>
<fileGrp USE="TEXT">
<file ID="BITSTREAM_TEXT_10366_135288_7" MIMETYPE="text/plain" SEQ="7" SIZE="72822" CHECKSUM="8fd75324a95a64d52e2b4efc812e9bce" CHECKSUMTYPE="MD5" ADMID="FT_10366_135288_7" GROUPID="GROUP_BITSTREAM_10366_135288_7">
<FLocat xlink:type="simple" LOCTYPE="URL" xlink:href="https://gredos.usal.es/bitstream/10366/135288/7/art5b_Vega%20Integrated%20design%20PART%20II_final.pdf.txt"/>
</file>
</fileGrp>
</fileSec>
<structMap TYPE="LOGICAL" LABEL="DSpace Object">
<div TYPE="DSpace Object Contents" ADMID="DMD_10366_135288">
<div TYPE="DSpace BITSTREAM">
<fptr FILEID="BITSTREAM_ORIGINAL_10366_135288_1"/>
</div>
</div>
</structMap>
</mets></metadata></record></GetRecord></OAI-PMH>