2026-08-25T21:39:56Zhttps://gredos.usal.es/oai/request

oai:gredos.usal.es:10366/1410022025-04-30T19:44:37Zcom_10366_4191com_10366_4055com_10366_3946com_10366_3823com_10366_4065com_10366_139852com_10366_4512col_10366_4192col_10366_4066col_10366_139853

Maisterra, Maitane Castro González, María Ángeles Muñoz Centeno, Luz María Calhelha, Ricardo C. Ferreira, Isabel Cristina Fernandes Rodrigues García García, Pablo Anselmo 2020-02-12T11:56:26Z 2020-02-12T11:56:26Z 2017 Maisterra, M., Castro, M. Á., Muñoz-Centeno, L. M., Calhelha, R. C., Ferreira, I. C., & García, P. A. (2017). Cytotoxic Terphenyl Neolignans from Fungus Terana coerulea: New Natural Corticins D and E, and Revised Structure for Corticin A. Natural product communications, 12(5), 1934578X1701200513. 1934-578X http://hdl.handle.net/10366/141002 10.1177/1934578X1701200513 1555-9475 [EN] The cobalt crust fungus Terana coerulea (Phanerochaetaceae family) was selected for a bio-guided study after an ethnobotanical survey at the Irati’s Forest (Navarra, Spain) for its local use as antibiotic. Six extracts of increasing polarity, from hexane to hot water, were obtained from powdered dry fungi and tested for cytotoxicity against four human tumour cell lines and one non-tumour primary cell culture. From the most cytotoxic, EtOAc extract, we isolated and identified three terphenyl neolignans: two of them new natural products, named corticins D and E, and one previously described as corticin A, whose earlier structure has been revised. Their structural elucidation and biological evaluation as cytotoxic agents are described. application/pdf eng Attribution-NonCommercial-NoDerivatives 4.0 Internacional http://creativecommons.org/licenses/by-nc-nd/4.0/ info:eu-repo/semantics/openAccess Grupo de Investigación en Biodiversidad, Sistemática y Conservación de Plantas Vasculares y Hongos Terana coerulea Terana caerulea Corticium caeruleum Neolignans Terphenyls Corticin Thelephoric acid Cytotoxic activity Fungus Navarra Fungi Terphenyl Compounds hongos compuestos de terfenilo Cytotoxic Terphenyl Neolignans from Fungus Terana coerulea: New Natural Corticins D and E, and Revised Structure for Corticin A info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion https://doi.org/10.1177/1934578X1701200513 Natural Product Communications 12 5 695 698