2026-04-17T06:13:33Zhttps://gredos.usal.es/oai/request

oai:gredos.usal.es:10366/1530792026-01-14T13:05:16Zcom_10366_153080com_10366_4512com_10366_3823com_10366_139417col_10366_166869col_10366_139418

Quintela Vega, Laura Morado Díaz, Camilo José Terreros, Gonzalo Sánchez Sánchez, Jazmín Pérez González, David Malmierca, Manuel S. Salamanca (España), lat=40,9701; long=-5,6635 start=10-2021 and end=10-2022 2023-09-26T10:28:25Z 2023-09-26T10:28:25Z 2023 http://hdl.handle.net/10366/153079 10.71636/r58m-w573 The tables from the file "Supplementary Tables" were obtained by the statistical analysis of the data from the Excel "Data Figures" [EN]The relative importance or saliency of sensory inputs depend on the animal’s environmental context and the behavioural responses to these same inputs can vary over time. Here we show how freely moving rats, trained to discriminate between deviant tones embedded in a regular pattern of repeating stimuli and different variations of the classic oddball paradigm, can detect deviant tones, and this discriminability resembles the properties that are typical of neuronal adaptation described in previous studies. Moreover, the auditory brainstem response (ABR) latency decreases after training, a finding consistent with the notion that animals develop a type of plasticity to auditory stimuli. Our study suggests the existence of a form of long-term memory that may modulate the level of neuronal adaptation according to its behavioural relevance, and sets the ground for future experiments that will help to disentangle the functional mechanisms that govern behavioural habituation and its relation to neuronal adaptation This work was supported by project PID2019-104570RB-I00 funded by MCIN/ AEI/10.13039/501100011033/ and The Foundation Ramón Areces grant CIVP20A6616 to MSM. LQ was supported by The Foundation Ramón Areces grant CIVP20A6616. CJMD held a Juan de la Cierva Fellowship (FJCI-2016-27897). DPG was supported by the European Union’s Horizon 2020 (H2020-WIDESPREAD-2020-5) programme, Grant agreement No.952378 BRAINTWIN. JSS holds the grant PRE2020-095617 funded by MCIN/AEI/ 10.13039/501100011033 and ESF eng Universidad de Salamanca https://gredos.usal.es/handle/10366/154982 PID2019-104570RB-I00 Attribution-NonCommercial-NoDerivatives 4.0 Internacional Attribution-NonCommercial-NoDerivatives 4.0 Internacional http://creativecommons.org/licenses/by-nc-nd/4.0/ info:eu-repo/semantics/openAccess Auditory Behavioural habituation Oddball paradigm Freely moving rats Novelty detection in an auditory oddball task on freely moving rats [Dataset] info:eu-repo/semantics/dataset info:eu-repo/semantics/submittedVersion 2023