2026-09-16T03:49:30Zhttps://gredos.usal.es/oai/request

oai:gredos.usal.es:10366/1541252025-04-30T20:39:56Zcom_10366_154031com_10366_4512com_10366_3823col_10366_154034

Contador Castillo, Israel Alzola, Patricia Stern, Yaakov Torre Luque, Alejandro de la Bermejo Pareja, Félix Fernández Calvo, Bernardino 2024-01-11T14:32:30Z 2024-01-11T14:32:30Z 2022-12-22 Contador, I., Alzola, P., Stern, Y., de la Torre-Luque, A., Bermejo-Pareja, F., & Fernández-Calvo, B. (2022). Is cognitive reserve associated with the prevention of cognitive decline after stroke? A Systematic review and meta-analysis. Ageing research reviews, 84, 101814. Advance online publication. https://doi.org/10.1016/j.arr.2022.101814 1568-1637 1872-9649 http://hdl.handle.net/10366/154125 10.1016/j.arr.2022.101814 [EN]Objective: To conduct a systematic review and meta-analyses of the effect of socio-behavioral cognitive reserve (CR) proxies on cognitive decline after stroke. Method: Three journal search and indexing databases (PubMed, Scopus and Web of Sciences) were crossed to examine the scientific evidence systematically. In addition, meta-analytic techniques, using mixed-effect methods, were carried out to estimate the impact (pooled effect size) of CR proxies on either dementia inci dence or cognitive decline after stroke. Results: Twenty-two studies were included in the systematic revision, whereas nineteen of them were eligible for the meta-analysis. The findings showed that high education is associated with a decreased rate of post-stroke dementia. Moreover, other CR proxies (e.g., occupation, bilingualism or social interaction) demonstrate a pro tective effect against non-dementia cognitive decline after stroke, although some inconsistencies were found in the literature. Regarding the meta-analysis, occupational attainment and education) showed a protective effect against post-stroke cognitive impairment diagnosis in comparison with a mixed category of different CR proxies. Second, a main cognitive change effect was found, pointing to greater cognitive change after stroke in those with low vs. high CR. Conclusions: Our findings emphasize that CR may prevent cognitive decline after stroke, but this effect can be modulated by different factors such the CR proxy and individual characteristics such as age or type of lesion. The methodological divergences of the studies (i.e., follow-up intervals, cognitive outcomes) need unification to diminish external sources of variability for predicting rates of cognitive decline after stroke. eng info:eu-repo/semantics/openAccess Cerebrovascular diseases Cognitive disorders Dementia Reserve Education Is cognitive reserve associated with the prevention of cognitive decline after stroke? A Systematic review and meta-analysis. info:eu-repo/semantics/article