2026-09-16T09:25:43Zhttps://gredos.usal.es/oai/request

oai:gredos.usal.es:10366/1541462025-04-30T19:37:27Zcom_10366_4019com_10366_3947com_10366_3946com_10366_3823col_10366_4020

Mirón Canelo, José Antonio Alonso Sardón, Montserrat Chamorro Fernández, Antonio Javier Hernández-García, Ignacio Iglesias de Sena, Helena Martín Rodero, Helena Herrera, Cristian Marcos Martín, Miguel 2024-01-11T17:15:50Z 2024-01-11T17:15:50Z 2015 Alonso-Sardón, M. Chamorro, A-J, Hernández-García, I.Iglesias-de-Sena, H. Martín Rodero, H. Herrera, C.et al. (2015). Association between Occupational Exposure to Wood Dust and Cancer: A Systematic Review and Meta-Analysis. PLoSONE, 10 (7), e0133024. doi:10.1371/journal. pone.013302 http://hdl.handle.net/10366/154146 10.1371/journal.pone.0133024 1932-6203 [EN]Objective: To perform a systematicr eview to analyze the association between occupational exposure to wood dust and cancer. Methods: A systematic literature search of entries made in the MEDLINE-Pub Med database between 1957and 2013 was conducted to identify studies that had assessed the relationship between occupational exposure to wood dust and different types of cancer. A meta-analysis of selected case-control and cohort studies was subsequently performed. Results: A total of 114 studies were identified and 70 were selected for review. Of these, 42 studies focused on the relationship between wood dust and nasal cancer (n=22), lung cancer (n= 11), and other types of cancer (n=9). Low-to-moderate quality evidence that wood dust acts as a carcinogen was obtained, and a stronger association between wood dust and nasal adenocarcinoma was observed. A lesser association between wood dust exposure and lung cancer was also observed. Several studies suggested that there is a relationship between wood dust and theo onset of other cancers,although therewas no evidence to establish an association. A meta-analysis that included four case-controls studies showed that workers exposed to wood dust exhibited higher rates of nasal adenocarcinoma than other workers (odds ratio=10.28;95% confidence interval:5.92 and 17.85;P<0,0001), although a large degree of heterogeneity was found. Conclusions Low-to-moderate quality evidence supports a causal association between cancer and occupational exposure to wood dust, and this association was stronger for nasal adenocarcinoma than for lung cancer. There was no evidence of an association between wood dust exposure and the other cancers examined. eng Public Library of Science Lung Neoplasms Nose Neoplasms Air Pollutants Occupational Diseases Lung Neoplasms Dust Air Pollutants, Occupational Nose Neoplasms 3213.05 Cirugía de Garganta, Nariz y Oídos neoplasias nasales contaminantes atmosféricos del entorno laboral neoplasias pulmonares polvo enfermedades profesionales Association between Occupational Exposure to Wood Dust and Cancer: A Systematic Review and Meta-Analysis info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion https://doi.org/10.1371/journal.pone.0133024 info:eu-repo/semantics/openAccess PLOS ONE 10 7 e0133024