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oai:gredos.usal.es:10366/1542432026-01-15T10:45:52Zcom_10366_4155com_10366_4055com_10366_3946com_10366_3823col_10366_4156

Benito Iglesias, David Herrero Teijón, Pablo Rubio González, María Rosa Fernández Mateos, Alfonso 2024-01-15T12:00:15Z 2024-01-15T12:00:15Z 2018 Benito Iglesias, D., Herrero Teijón, P., Rubio González, R. & Fernández Mateos, A. (2018). Synthesis of trans‐β‐Elemene. European Journal of Organic Chemistry, 2018(35), 4926–4932. https://doi.org/10.1002/ejoc.201800800 1434-193X http://hdl.handle.net/10366/154243 10.1002/ejoc.201800800 1099-0690 [EN]Highly efficient syntheses of the anti-cancer agent trans-β-elemene have been achieved by using the readily available (±)-limonene as starting material. The syntheses were achieved in only nine to eleven steps with good overall yields. The key step in these reaction sequences is a stereoselective radical cyclization, induced by titanocene chloride. application/pdf eng Wiley Attribution-NonCommercial-NoDerivatives 4.0 Internacional http://creativecommons.org/licenses/by-nc-nd/4.0/ info:eu-repo/semantics/openAccess Química orgánica Anticancerosos Radicales (Química) Cloruros 2306 Química Orgánica Synthesis of trans‐β‐Elemene info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion https://doi.org/10.1002/ejoc.201800800 European Journal of Organic Chemistry 2018 35 4926 4932