2026-09-14T20:24:06Zhttps://gredos.usal.es/oai/requestoai:gredos.usal.es:10366/1547542025-04-30T20:18:27Zcom_10366_4368com_10366_4349com_10366_3946com_10366_3823col_10366_4369
Gestión del Repositorio Documental de la Universidad de Salamanca
author
Martínez-Vázquez, Francisco J.
author
Perera Martínez, Fidel Hugo
author
Meulen, Inge van der
author
Heise, Andreas
author
Pajares, Antonia
author
Miranda, Pedro
2024-01-25T12:15:39Z
2024-01-25T12:15:39Z
2013
Martínez‐Vázquez, F. J., Perera, F. H., Van Der Meulen, I., Heise, A., Pajares, A., & Miranda, P. (2013). Impregnation of Β‐tricalcium phosphate robocast scaffolds by in situ polymerization. Journal of Biomedical Materials Research Part A, 101(11), 3086-3096. https://doi.org/10.1002/jbm.a.34609
1549-3296
http://hdl.handle.net/10366/154754
10.1002/JBM.A.34609
1552-4965
[EN]Ring-opening polymerization ofe-caprolactone (e-CL) andL-lactide (LLA) was performed to impregnateb-trical-cium phosphate (b-TCP) scaffolds fabricated by robocasting.Concentrated colloidal inks prepared fromb-TCP commercialpowders were used to fabricate porous structures consistingof a 3D mesh of interpenetrating rods.e-CL and LLA wereinsitupolymerized within the ceramic structure by using alipase and stannous octanoate, respectively, as catalysts. Theresults show that both the macropores inside the ceramicmesh and the micropores within the ceramic rods are full ofpolymer in either case. The mechanical properties of scaf-folds impregnated byin situpolymerization (ISP) are signifi-cantly increased over those of the bare structures, exhibiting similar values than those obtained by other, more aggres-sive, impregnation methods such as melt-immersion (MI).ISP using enzymatic catalysts requires a reduced processingtemperature which could facilitate the incorporation ofgrowth factors and other drugs into the polymer composi-tion, thus enhancing the bioactivity of the composite scaffold.The implications of these results for the optimization of themechanical and biological performance of scaffolds for bonetissue engineering applications are discussed.
eng
Attribution-NonCommercial-NoDerivatives 4.0 Internacional
Ring opening polymerization
Polymer impregnation
Robocasting
Scaffolds
Mechanical properties
Impregnation of β‐tricalcium phosphate robocast scaffolds by in situ polymerization
info:eu-repo/semantics/article
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https://gredos.usal.es/bitstream/10366/154754/1/DIM_Impregnation%20of%20b-tricalcium.pdf
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DIM_Impregnation of b-tricalcium.pdf.txt