2026-09-14T15:32:22Zhttps://gredos.usal.es/oai/request

oai:gredos.usal.es:10366/1549822025-07-11T11:52:53Zcom_10366_4613com_10366_4576com_10366_3823col_10366_4616

Quintela-Vega, Laura Morado-Díaz, Camilo J. Terreros, Gonzalo Sánchez Sánchez, Jazmín Pérez González, David Malmierca, Manuel S. 2024-01-30T09:32:29Z 2024-01-30T09:32:29Z 2023-10-23 http://hdl.handle.net/10366/154982 10.1038/s42003-023-05403-y 2399-3642 The relative importance or saliency of sensory inputs depend on the animal’s environmental context and the behavioural responses to these same inputs can vary over time. Here we show how freely moving rats, trained to discriminate between deviant tones embedded in a regular pattern of repeating stimuli and different variations of the classic oddball paradigm, can detect deviant tones, and this discriminability resembles the properties that are typical of neuronal adaptation described in previous studies. Moreover, the auditory brainstem response (ABR) latency decreases after training, a finding consistent with the notion that animals develop a type of plasticity to auditory stimuli. Our study suggests the existence of a form of long-term memory that may modulate the level of neuronal adaptation according to its behavioural relevance, and sets the ground for future experiments that will help to dis- entangle the functional mechanisms that govern behavioural habituation and its relation to neuronal adaptation. eng info:eu-repo/semantics/openAccess Audición Plasticidad neuronal Detección Animal experimentation Novelty detection in an auditory oddball task on freely moving rats info:eu-repo/semantics/article