2026-09-15T21:36:25Zhttps://gredos.usal.es/oai/requestoai:gredos.usal.es:10366/1552382026-01-14T09:50:18Zcom_10366_4182com_10366_4055com_10366_3946com_10366_3823col_10366_4183
Evaluation of the sample treatment influence in green and sustainable assessment of liquid chromatography methods by the HEXAGON tool: Sulfonate-based dyes determination in meat samples
Ballester-Caudet, Ana
Navarro-Utiel, R.
Campos-Hernández, I.
Campíns-Falcó, Pilar
Hexagon pictogram
Greenness
Sustainability
Miniaturization
In-tube SPME
Food
Dyes
[EN] Green and Sustainable assessment of sample treatment has been carried out when using liquid chromatographic methods in food analysis. Particularly, published sulfonate-based dyes determination by conventional liquid chromatography with diode array (HPLC-DAD) or mass detectors (HPLC-MS/MS) was selected as starting point. Greenness-sustainability have been quantitatively evaluated by means of the HEXAGON tool, in which sample treatment and method characteristics noticeably play a key role in defining the figures of merit of the analytical procedure. According to the evaluation results that are represented in a hexagon pictogram with an overall score from 0 to 4 (the lower the score, the greater contribution), a new analytical method is proposed by means of both minimizing and miniaturizing sample treatment step. In-tube solid-phase microextraction online coupled to capillary LC (IT-SPME-CapLC-DAD) provided a more green and sustainable alternative to current food dyes analysis without losing sensitivity (LODs 0.5-1 μg/g sample). The proposed method was tested on chicken meat samples (2 g), using ethanol-ammonia-water mixture (80:1:19, v/v/v; 5 mL) as extraction solution. The arithmetic means of the HEXAGON scores (s av ) were: 1.71, 2.57 and 2.71 for IT-SPME-CapLC-DAD, HPLC-DAD and HPLC-MS/MS, respectively. The proposed method was closer than the others tested to a hypothetical LC procedure without sample treatment, which provided a s av value of 1.
2024-02-02T16:58:09Z
2024-02-02T16:58:09Z
2022
info:eu-repo/semantics/article
A. Ballester-Caudet, R. Navarro-Utiel, I. Campos-Hernández, P. Campíns-Falcó,
Evaluation of the sample treatment influence in green and sustainable assessment of liquid chromatography methods by the HEXAGON tool: Sulfonate-based dyes determination in meat samples,
Green Analytical Chemistry,
Volume 3,
2022,
100024,
ISSN 2772-5774,
https://doi.org/10.1016/j.greeac.2022.100024.
(https://www.sciencedirect.com/science/article/pii/S2772577422000234)
2772-5774
http://hdl.handle.net/10366/155238
10.1016/j.greeac.2022.100024
eng
https://doi.org/10.1016/j.greeac.2022.100024
http://creativecommons.org/publicdomain/zero/1.0/
info:eu-repo/semantics/openAccess
CC0 1.0 Universal
Elsevier