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oai:gredos.usal.es:10366/1564892025-04-30T19:41:22Zcom_10366_4028com_10366_3947com_10366_3946com_10366_3823col_10366_4029

00925njm 22002777a 4500 dc Moreno, Edgardo author Middlebrook, Earl A. author Altamirano-Silva, Pamela author Al Dahouk, Sascha author Araj, George F. author Arce-Gorvel, Vilma author Arenas-Gamboa, Ángela author Ariza, Javier author Barquero-Calvo, Elías author Battelli, Giorgio author Bertu, Wilson J. author Blasco, José María author Bosilkovski, Mile author Cadmus, Simeon author Caswell, Clayton C. author Celli, Jean author Chacón-Díaz, Carlos author Chaves-Olarte, Esteban author Comerci, Diego J. author Conde-Álvarez, Raquel author Cook, Elizabeth author Cravero, Silvio author Dadar, Maryam author De Boelle, Xavier author De Massis, Fabrizio author Díaz, Ramón author Escobar, Gabriela I. author Ficht, Thomas A. author Foster, Jeffrey T. author Garin-Bastuji, Bruno author Godfroid, Jacques author Gorvel, Jean-Pierre author Güler, Leyla author Erdenliğ-Gürbilek, Sevil author Gusi, Amayel M. author Guzmán-Verri, Caterina author Hai, Jiang author Hernández-Mora, Gabriela author Iriarte, Maite author Jacob, Nestor R. author Keriel, Anne author Khames, Maamar author Köhler, Stephan author Letesson, Jean-Jacques author Loperena-Barber, Maite author López-Goñi, Ignacio author McGiven, John author Melzer, Falk author Mora-Cartin, Ricardo author Moran-Gilad, Jacob author Muñoz, Pilar M. author Neubauer, Heinrich author O'Callaghan, David author Ocholi, Reuben author Oñate, Ángel author Pandey, Piyush author Pappas, Georgios author Pembroke, J. Tony author Roop, Martin author Ruiz-Villalonos, Nazaret author Ryan, Michael P. author Salcedo, Suzana P. author Salvador-Bescós, Miriam author Sangari, Félix J. author de Lima Santos, Renato author Seimenis, Aristarchos author Splitter, Gary author Suárez-Esquivel, Marcela author Tabbaa, Darem author Trangoni, Marcos David author Tsolis, Renee M. author Vizcaino Santiso, Nieves author Wareth, Gamal author Welburn, Susan C. author Whatmore, Adrian author Zúñiga-Ripa, Amaia author Moriyón, Ignacio author Fernández Lago, Luis Román author 2023 [EN]Bacteria of the genus Brucella are facultative intracellular parasites that cause brucellosis, a severe animal and human disease. Recently, a group of taxonomists merged the brucellae with the primarily free-living, phylogenetically related Ochrobactrum spp. in the genus Brucella. This change, founded only on global genomic analysis and the fortuitous isolation of some opportunistic Ochrobactrum spp. from medically compromised patients, has been automatically included in culture collections and databases. We argue that clinical and environmental microbiologists should not accept this nomenclature, and we advise against its use because (i) it was presented without in-depth phylogenetic analyses and did not consider alternative taxonomic solutions; (ii) it was launched without the input of experts in brucellosis or Ochrobactrum; (iii) it applies a non-consensus genus concept that disregards taxonomically relevant differences in structure, physiology, population structure, core-pangenome assemblies, genome structure, genomic traits, clinical features, treatment, prevention, diagnosis, genus description rules, and, above all, pathogenicity; and (iv) placing these two bacterial groups in the same genus creates risks for veterinarians, medical doctors, clinical laboratories, health authorities, and legislators who deal with brucellosis, a disease that is particularly relevant in low- and middle-income countries. Based on all this information, we urge microbiologists, bacterial collections, genomic databases, journals, and public health boards to keep the Brucella and Ochrobactrum genera separate to avoid further bewilderment and harm. Moreno, E., Middlebrook, E. A., Altamirano-Silva, P., Al Dahouk, S., Araj, G. F., Arce-Gorvel, V., ... & Moriyón, I. (2023). If you're not confused, you're not paying attention: Ochrobactrum is not Brucella. Journal of clinical microbiology, 61(8), e00438-23. 0095-1137 http://hdl.handle.net/10366/156489 10.1128/jcm.00438-23 1098-660X Ochrobactrum spp Brucella brucelosis parásitos intracelulares diferencias taxonómicas If You're Not Confused, You're Not Paying Attention : Ochrobactrum Is Not Brucella