2026-09-17T03:16:15Zhttps://gredos.usal.es/oai/request

oai:gredos.usal.es:10366/1618452025-04-30T19:35:20Zcom_10366_4019com_10366_3947com_10366_3946com_10366_3823col_10366_4020

00925njm 22002777a 4500 dc López-Sánchez, Jaime author Esteban, Carmen author Iglesias Iglesias, Manuel José author González, Luis M author Quiñones, José E author González Muñoz, Juan Ignacio author Tabernero Fernández, Guadalupe author Iglesias, Rosa A author Fraile Gómez, María Pilar author Muñoz Bellvís, Luis author Muñoz González, Javier Ignacio author 2021-05 [EN]Pancreas transplantation (PT) is one of the few ways to restore euglycemia within diabetic patients; however, the high morbidity caused by surgical complications and the need for immunosuppressive therapy has raised controversy about PT improving the health-related quality-of-life (HRQoL). The aim of this study is to assess the long-term (≥ 5 years after PT) HRQoL and to identify the factors affecting it. A single-center, cross-sectional study of 49 sequential PT was performed. All patients conducted a telephone interview to fulfill the modification of Medical Outcome Health Survey Short Form questionnaire (SF-36v2) and were compared to similar post-PT studies from the literature. Patients with a history of replacement renal therapy (RRT) or neuropathy undergoing a PT were associated to a worse bodily pain (P = 0.03) and physical function (P = 0.04), respectively, whereas those with retinopathy showed an improved Role Emotional (P = 0.04). Multivariate analysis revealed the presence of RRT as the only independent prognostic factor for a worse bodily pain [relative risk = 3.9; 95% confidence interval (1.1-14.6)], (P = 0.04). Furthermore, nearly all PT recipients (91.8%) claimed an overall better health than prior to PT. Our study confirms that PT recipients' HRQoL improves after PT, showing similar HRQoL scores across different populations and suggests that patients in predialysis could benefit from an improved HRQoL if transplanted on the early stages of the disease. López-Sánchez, J., Esteban, C., Iglesias, M. J., González, L. M., Quiñones, J. E., González-Muñoz, J. I., Tabernero, G., Iglesias, R. A., Fraile, P., Muñoz-González, J. I., & Muñoz-Bellvís, L. (2021). Factors affecting diabetic patient's long-term quality of life after simultaneous pancreas-kidney transplantation: a single-center analysis. Langenbeck's archives of surgery, 406(3), 873–882. https://doi.org/10.1007/s00423-020-02059-8 1435-2443 http://hdl.handle.net/10366/161845 10.1007/s00423-020-02059-8 33416988 1435-2451 Pancreas transplantation Simultaneous pancreas-kidney transplantation Predialysis Health-related quality-of-life Factors affecting diabetic patient's long-term quality of life after simultaneous pancreas-kidney transplantation: a single-center analysis.