<?xml version="1.0" encoding="UTF-8"?><?xml-stylesheet type="text/xsl" href="static/style.xsl"?><OAI-PMH xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/ http://www.openarchives.org/OAI/2.0/OAI-PMH.xsd"><responseDate>2026-09-17T06:21:27Z</responseDate><request verb="GetRecord" identifier="oai:gredos.usal.es:10366/163541" metadataPrefix="etdms">https://gredos.usal.es/oai/request</request><GetRecord><record><header><identifier>oai:gredos.usal.es:10366/163541</identifier><datestamp>2025-04-30T19:27:34Z</datestamp><setSpec>com_10366_3974</setSpec><setSpec>com_10366_3947</setSpec><setSpec>com_10366_3946</setSpec><setSpec>com_10366_3823</setSpec><setSpec>col_10366_3975</setSpec></header><metadata><thesis xmlns="http://www.ndltd.org/standards/metadata/etdms/1.0/" xmlns:doc="http://www.lyncode.com/xoai" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.ndltd.org/standards/metadata/etdms/1.0/ http://www.ndltd.org/standards/metadata/etdms/1.0/etdms.xsd">
<title>Early diagnosis of central disorders mimickig hornizontal canal cupulolithiasis</title>
<creator>Peña Navarro, Paula</creator>
<creator>Pachecho López, Sofía</creator>
<creator>Almeida Ayerve, Cristina Nicole</creator>
<creator>Marcos Alonso, Susana</creator>
<creator>Serradilla López, José Manuel</creator>
<creator>Santa Cruz Ruiz, Santiago</creator>
<creator>Gómez Sánchez, José Carlos</creator>
<creator>Kaski, Diego</creator>
<creator>Batuecas Caletrio, Ángel</creator>
<subject>Benign paroxysmal positional vertigo</subject>
<subject>Horizontal semicircular canal</subject>
<subject>Central positional nystagmus</subject>
<subject>Differential diagnosis</subject>
<description>[EN]Abstract: Background: Horizontal Canal Cupulolithiasis (hc-BPPV-cu) can mimic a pathology of&#xd;
central origin, so a careful examination is essential to prevent misdiagnosis. Methods: Retrospective&#xd;
cross-sectional cohort study of 45 patients suffering from suspected hc-BPPV-cu. We recorded whether&#xd;
patients first presented through an ENT Emergency Department (ED) or through an Outpatient&#xd;
Otolaryngology Clinic (OC). Results: We found statistically significant differences (p &lt; 0.05) between&#xd;
the OC versus the ED in relation to the time between symptom onset and first assessment (79.7 vs.&#xd;
3.6 days, respectively), the number of therapeutic maneuvers (one maneuver in 62.5% vs. 75.9%, and&#xd;
more than one in 25.1% vs. 13.7%), and multi-canal BPPV rate (43.8% vs. 3.4%). hc-BPPV-cu did not&#xd;
resolve in 2 patients (12.5%) from the OC and in 3 (10.3%) from de ED, all of which showed central&#xd;
pathology. Discussion: There are no prior studies that analyze the approach to hc-BPPV-cu in the&#xd;
ED. The benefits of early specialist input are early identification of central positional nystagmus, a&#xd;
decrease in symptom duration, reduced number of therapeutic maneuvers required for symptom&#xd;
resolution, and lower rates of iatrogenic multi-canal BPPV. Conclusion: A comprehensive approach&#xd;
to hc-BPPV-cu in the ED allows both more effective treatment and early identification of central&#xd;
disorder mimics.</description>
<date>2025-02-06</date>
<date>2025-02-06</date>
<date>2023</date>
<type>info:eu-repo/semantics/article</type>
<identifier>Peña Navarro, P., Pacheco López, S., Almeida Ayerve, C. N., Marcos Alonso, S., Serradilla López, J. M., Santa Cruz Ruiz, S., Gómez Sánchez, J. C., Kaski, D., &amp; Batuecas Caletrío, Á. (2023). Early Diagnosis of Central Disorders Mimicking Horizontal Canal Cupulolithiasis. Brain Sciences, 13(4). https://doi.org/10.3390/BRAINSCI13040562</identifier>
<identifier>http://hdl.handle.net/10366/163541</identifier>
<identifier>10.3390/brainsci13040562</identifier>
<identifier>2076-3425</identifier>
<language>eng</language>
<relation>https://www.mdpi.com/2076-3425/13/4/562</relation>
<rights>info:eu-repo/semantics/openAccess</rights>
<publisher>MDPI</publisher>
</thesis></metadata></record></GetRecord></OAI-PMH>