2026-09-16T01:47:15Zhttps://gredos.usal.es/oai/request

oai:gredos.usal.es:10366/1635542026-02-20T11:42:03Zcom_10366_3974com_10366_3947com_10366_3946com_10366_3823col_10366_3975

Marcos-Alonso, Susana Ayerve, Nicole Almeida Roca, Chiara Monopoli Touma, Guillermo Coronel Pozo de Dios, Juan Carlos del Sánchez Gómez, Hortensia Ruíz, Santiago Santa Cruz Batuecas Caletrio, Ángel 2025-02-06T12:34:46Z 2025-02-06T12:34:46Z 2023-08-16 Alonso, S. M., Ayerve, N. A., Roca, C. M., Touma, G. C., de Dios, J. C. D. P., Gómez, H. S., ... & Caletrío, Á. B. (2023). Use of Skull Vibration-Induced Nystagmus in the Follow-up of Patients With Ménière Disease Treated With Intratympanic Gentamicin. Clinical and Experimental Otorhinolaryngology, 16(3), 236-243. 1976-8710 http://hdl.handle.net/10366/163554 10.21053/ceo.2023.00129 2005-0720 [EN]Objectives. Ménière disease (MD) is an idiopathic disorder that affects hearing and inner ear balance. Intratympanic genta-micin (ITG) is recognized as an effective treatment for uncontrolled MD characterized by persistent vertigo attacks despite therapy.The video head impulse test (vHIT) and skull vibration-induced nystagmus (SVIN) are validated methods for evaluating vestibular function. A progressive linear relationship has been identified between the slow-phase velocity (SPV) of SVIN determined using a 100-Hz skull vibrator and the gain difference (healthy ear/affected ear) measured by vHIT.The aim of this study was to ascertain whether the SPV of SVIN was associated with the recovery of vestibular function following ITG treatment. Consequently, we sought to determine whether SVIN could predict the onset of new vertigo attacks in patients with MD who were treated with ITG. Methods. A prospective longitudinal case-control study was conducted. Several variables were recorded post-ITG and through-out the follow-up period, followed by statistical analyses. Two groups were compared: patients who experienced vertigo attacks 6 months after ITG and those who did not. Results. The sample comprised 88 patients diagnosed with MD who underwent ITG treatment. Of the 18 patients who experienced recurring vertigo attacks, 15 demonstrated gain recovery in the affected ear. However, all 18 patients ex-hibited a decrease in the SPV of SVIN. Conclusion. The SPV of SVIN may be more sensitive than vHIT in identifying the recovery of vestibular function following ITG administration. To our knowledge, this is the first study to illustrate the link between a reduction in SPV and the likelihood of vertigo episodes in patients with MD who have been treated with ITG. eng Clinical and Experimental Otorhinolaryngology Attribution-NonCommercial-NoDerivatives 4.0 Internacional http://creativecommons.org/licenses/by/4.0/ info:eu-repo/semantics/openAccess Pathologic Nystagmus Vestibular Disease Meniere Disease Gentamicin Head Impulse Test Gentamicins Head Impulse Test Vestibular Diseases 2411.13 Fisiología de la Audición 3205 Medicina Interna enfermedades vestibulares prueba de impulso cefálico gentamicinas Use of skull vibration-induced nystagmus in the follow-up of patients with Ménière disease treated with intratympanic gentamicin info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion https://doi.org/10.21053/ceo.2023.00129 Clinical and Experimental Otorhinolaryngology 16 3 236 243