2026-09-15T04:54:53Zhttps://gredos.usal.es/oai/request
oai:gredos.usal.es:10366/1668012025-08-28T00:02:53Zcom_10366_4313com_10366_4200com_10366_3946com_10366_3823col_10366_4314
Gestión del Repositorio Documental de la Universidad de Salamanca author Villanueva, Vicente author Artal, Jesús Ángel author Cabeza Alvarez, Clara Isabel author Campos, Dulce author Castillo, Ascensión author Flórez, Gerardo author Franco Martín, Manuel Ángel author García-Portilla, María Paz author Giráldez, Beatriz G. author Gotor, Francisco author Gutiérrez-Rojas, Luis author Albanell, Albert Molins author Paniagua, Gonzalo author Pintor, Luis author Poza, Juan José author Rubio-Granero, Teresa author Toledo, Manuel author Tortosa-Conesa, Diego author Rodríguez-Uranga, Juan author Bobes, Julio 2025-08-26T06:44:39Z 2025-08-26T06:44:39Z 2023 Villanueva, V., Artal, J., Cabeza-Alvarez, C.-I., Campos, D., Castillo, A., Flórez, G., Franco-Martin, M., García-Portilla, M. P., Giráldez, B. G., Gotor, F., Gutiérrez-Rojas, L., Albanell, A. M., Paniagua, G., Pintor, L., Poza, J. J., Rubio-Granero, T., Toledo, M., Tortosa-Conesa, D., Rodríguez-Uranga, J., … Bobes, J. (2023). Proposed Recommendations for the Management of Depression in Adults with Epilepsy: An Expert Consensus. Neurology and Therapy, 12(2), 479-503. https://doi.org/10.1007/S40120-023-00437-0 2193-8253 http://hdl.handle.net/10366/166801 10.1007/s40120-023-00437-0 2193-6536 [EN]Introduction: Experts agree that there is a need for protocols to guide health professionals on how to best manage psychiatric comorbidities in patients with epilepsy (PWE). We aimed to develop practical recommendations for key issues in the management of depression in PWE. Methods: This was a qualitative study conducted in four steps: (1) development of a questionnaire on the management of depression in PWE to be answered; (2) literature review and, if evidence from guidelines/consensus or systematic reviews was available, drafting initial recommendations; (3) a nominal group methodology for reviewing initial recommendations and formulating new recommendations on those issues without available evidence; and (4) drafting and approving the final recommendations. A scientific committee (one neurologist and one psychiatrist) was responsible for the development of the project and its scientific integrity. The scientific committee selected a panel of experts (nine neurologists and nine psychiatrists with experience in this field) to be involved in the nominal group meetings and to formulate final recommendations. Results: Fifteen recommendations were formulated. Four on the screening and diagnosis: screening and diagnosis of depression, evaluation of the risk of suicide, and diagnosis of depression secondary to epilepsy; nine on the management of depression: referral to a psychiatrist, selection of the antiseizure medication, change of antiseizure medication, antidepressant treatment initiation, selection of antidepressant, use of antidepressants during pregnancy, use of psychotherapy, antidepressant treatment duration, and discontinuation of antidepressant treatment; two on the follow-up: duration of the follow-up under usual conditions, and follow-up of patients at risk of suicide. Conclusion: We provide recommendations based on expert opinion consensus to help healthcare professionals assess depression in PWE. The detection and treatment of major depressive disorders are key factors in improving epilepsy outcomes and avoiding suicide risk. eng Attribution-NonCommercial-NoDerivatives 4.0 Internacional Depression Diagnosis Epilepsy Expert consensus Suicide risk Treatment Proposed Recommendations for the Management of Depression in Adults with Epilepsy: An Expert Consensus info:eu-repo/semantics/article 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 URL https://gredos.usal.es/bitstream/10366/166801/1/Proposed%20Recommendations%20for%20the%20Management%20of%20Depression%20in%20Adults%20with%20Epilepsy.%20An%20Expert%20Consensus.pdf File MD5 ca9108f5259070e5f4545ce1e83b53c0 537679 application/pdf Proposed Recommendations for the Management of Depression in Adults with Epilepsy. An Expert Consensus.pdf URL https://gredos.usal.es/bitstream/10366/166801/4/Proposed%20Recommendations%20for%20the%20Management%20of%20Depression%20in%20Adults%20with%20Epilepsy.%20An%20Expert%20Consensus.pdf.txt File MD5 0e2f5d705bb1ba6e46cec0e23212c6a9 76607 text/plain Proposed Recommendations for the Management of Depression in Adults with Epilepsy. An Expert Consensus.pdf.txt