2026-09-15T05:37:38Zhttps://gredos.usal.es/oai/request

oai:gredos.usal.es:10366/1679712026-02-17T09:57:15Zcom_10366_154570com_10366_4512com_10366_3823com_10366_3974com_10366_3947com_10366_3946col_10366_154571col_10366_3975

00925njm 22002777a 4500 dc Lorente-Piera, Joan author Blanco, Melissa author Manrique-Huarte, Raquel author David, Adriana author Suárez Vega, Víctor Manuel author Batuecas Caletrio, Ángel author Liaño Esteve, Gloria author Domínguez, Pablo author Pérez Fernández, Nicolás author 2025-09-28 [EN]Background/Objectives: Skull vibration-induced nystagmus (SVIN) is a rapid bedside test that reveals vestibular asymmetry. Its clinical utility in Ménière's disease (MD) remains controversial, particularly regarding its association with radiological endolymphatic hydrops (EH). This study aimed to evaluate the relationship between SVIN, audiovestibular parameters, and EH severity in patients with unilateral definite MD. Methods: This prospective observational study was conducted at a tertiary academic referral center and included patients with unilateral MD who underwent SVIN testing (SVT), audiovestibular evaluation (PTA, cVEMP, oVEMP, vHIT, and caloric testing), and 3T MRI with gadolinium-enhanced 3D-FLAIR sequences to quantify EH. Results: In total, 84 patients were included in the study. SVIN was present in 57.14% of patients (n = 48), with ipsilesional nystagmus being the most frequent subtype (64.58%). Patients with SVIN had significantly higher vestibular EH (p = 0.017) and vestibular endolymphatic ratio (REL) in the affected ear (p = 0.019). Disease duration (p = 0.026) and shorter time since last vertigo spell (p = 0.018) were also associated with SVIN presence. REL correlated moderately with disease duration (r = 0.390, p < 0.001), PTA (r = 0.576, p < 0.001), and number of vertigo spells (r = 0.236, p = 0.031), but not with time since last crisis (r = -0.127, p = 0.252). ROC analysis yielded an AUC of 0.735 for REL in predicting SVIN. Conclusions: SVIN correlates with the severity of vestibular EH. This finding indicates a stimulus-locked response of a vestibular asymmetry rather than a purely structural alteration. Lorente-Piera, J., Blanco, M., Manrique-Huarte, R., David, A., Suarez-Vega, V., Batuecas-Caletrío, A., Esteve, G. L., Dominguez, P., & Pérez-Fernández, N. (2025). Vibration-Induced Nystagmus in Patients with Ménière’s Disease: Is There a Correlation to Endolymphatic Hydrops? Audiology Research, 15(5). https://doi.org/10.3390/AUDIOLRES15050125 2039-4330 http://hdl.handle.net/10366/167971 10.3390/audiolres15050125 41148751 2039-4349 Ménière disease Vibration induced nystagmus Endolymphatic hydrops Perilymphatic enhancement Vestibular herniation Vibration-induced nystagmus in patients with Ménière's disease: Is there a correlation to endolymphatic hydrops?