2026-09-16T03:07:53Zhttps://gredos.usal.es/oai/request

oai:gredos.usal.es:10366/1686012026-01-10T01:02:25Zcom_10366_4182com_10366_4055com_10366_3946com_10366_3823col_10366_4183

Bustamante Rángel, Myriam Nogal Sánchez, Miguel del García García, Samuel Conejo-Valverde, P. Rodríguez Gonzalo, Encarnación Pérez Pavón, José Luis 2026-01-09T12:43:45Z 2026-01-09T12:43:45Z 2024 M. Bustamante-Rangel, M. del Nogal Sánchez, S. García-García, P. Conejo-Valverde, E. Rodríguez-Gonzalo, J.L. Pérez Pavón, A new method based on dispersive solid phase microextraction with commercial MOFs coupled to LC-MS/MS for the determination of isoflavones in soy drinks, Food Chemistry, Volume 455, 2024, 139861, ISSN 0308-8146, https://doi.org/10.1016/j.foodchem.2024.139861. (https://www.sciencedirect.com/science/article/pii/S0308814624015115) 0308-8146 http://hdl.handle.net/10366/168601 10.1016/j.foodchem.2024.139861 [EN]For the first time, a method based on dispersive solid phase microextraction (D-μSPE) using commercial metal-organic frameworks coupled to liquid chromatography-triple quadrupole tandem mass spectrometry (LC–MS/MS) has been proposed for the determination of isoflavones in soy drinks. The use of commercial sorbents simplifies the sample treatment procedure and allows their application to routine analysis. Optimization of the parameters involved in the microextraction process was carried out using a Box-Behnken experimental design. Under the optimized conditions, the limits of detection ranged between 2 and 7 μg L−1; the intra-day and inter-day precision were <10 and 20%, respectively, and the recoveries were in the range of 61–120%. No significant matrix effect was found, which allowed the use of external standard calibration method. The method was successfully applied to the determination of isoflavones in commercial soy milk samples. eng Elsevier Attribution-NonCommercial-NoDerivatives 4.0 Internacional http://creativecommons.org/licenses/by-nc-nd/4.0/ info:eu-repo/semantics/openAccess Dispersive solid phase microextraction MOFs LC-MS/MS Isoflavones Soy drinks A new method based on dispersive solid phase microextraction with commercial MOFs coupled to LC-MS/MS for the determination of isoflavones in soy drinks info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion https://doi.org/10.1016/j.foodchem.2024.139861 Spanish Ministry of Science and Innovation (Project PID2021-127679NB-100) Food Chemistry 455 139861