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<title>A Home-Based Interdisciplinary Intervention to Enhance Functionality in Oncology Patients: Results from a Clinical Trial</title>
<creator>Fernández Rodríguez, Eduardo José</creator>
<creator>Sánchez Gómez, Celia</creator>
<creator>Rihuete Galve, María Isabel</creator>
<creator>Fonseca Sánchez, Emilio</creator>
<creator>Cruz Hernández, Juan Jesús</creator>
<subject>Quality of life</subject>
<subject>Oncology patients</subject>
<subject>Dyspnoea</subject>
<subject>Cancer rehabilitation</subject>
<description>[EN]Background/Objectives: Dyspnoea and functional decline are common among cancer patients with associated respiratory conditions. This study aimed to evaluate the effectiveness of an Effort Re-education Programme (ERP) in improving functionality and quality of life in hospitalised oncology patients compared to Conventional Clinical Practice (CCP). Methods: A stratified, randomised, prospective clinical trial was conducted involving 65 patients with cancer and associated respiratory conditions. Participants were assigned to either a control group (CCP) or an experimental group (ERP + CCP). Functionality (Barthel Index), health-related quality of life (EORTC QLQ-C30), overall performance (Karnofsky Scale), and instrumental activities of daily living (Lawton and Brody Scale) were assessed at baseline and one month post-discharge. Results: The ERP group showed significantly greater improvements in all outcome measures: Barthel Index (mean change: +18.33 vs. +6.19), EORTC QLQ-C30 (+16.4 vs. +6.6), Karnofsky (+18.75 vs. +5.6), and Lawton–Brody (+2.78 vs. +0.78), all with p &lt; 0.001 and moderate-to-large effect sizes (Cohen’s d = 0.72–1.19). No readmissions were reported in the ERP group, versus 37.5% in the control group. Conclusions: The ERP significantly improves basic and instrumental functionality, autonomy, and health-related quality of life in oncology patients with respiratory conditions. These findings support the integration of Functional Re-education Programmes into routine clinical practice as a complement to standard care.</description>
<date>2026-01-26</date>
<date>2026-01-26</date>
<date>2025-06-20</date>
<type>info:eu-repo/semantics/article</type>
<identifier>Eduardo José Fernández-Rodríguez, Sánchez-Gómez, C., Maria Isabel Rihuete-Galve, Fonseca-Sánchez, E., &amp; Juan Jesús Cruz-Hernández. (2025). A Home-Based Interdisciplinary Intervention to Enhance Functionality in Oncology Patients: Results from a Clinical Trial. Journal of Clinical Medicine, 14(13), 4417. https://doi.org/10.3390/JCM14134417</identifier>
<identifier>2077-0383</identifier>
<identifier>http://hdl.handle.net/10366/169270</identifier>
<identifier>10.3390/jcm14134417</identifier>
<language>eng</language>
<relation>https://www.mdpi.com/2077-0383/14/13/4417</relation>
<rights>info:eu-repo/semantics/openAccess</rights>
<publisher>MDPI</publisher>
</thesis></metadata></record></GetRecord></OAI-PMH>