2026-09-15T06:00:07Zhttps://gredos.usal.es/oai/requestoai:gredos.usal.es:10366/1710242026-04-18T00:01:13Zcom_10366_4173com_10366_4055com_10366_3946com_10366_3823col_10366_4174
Effect of the structure and concentration of cyclodextrins in the quenching process of naproxen
Valero Juan, Margarita
López Cornejo, M. P.
Costa, S.M.B.
López Cornejo
Quenching
Naproxen
Hydroxypropyl
alpha-Cyclodextrins
beta-Cyclodextrins
[EN]The effect of the formation of the naproxen:cyclodextrin inclusion complex on the quenching of the drug by iodide has been studied. The results
show that -cyclodextrin ( -CD), -cyclodextrin ( -CD), and hydroxypropyl- -cyclodextrin (HP- -CD) provide good protection for the drug
against iodide quenching. The trend of protection is -CD > HP- -CD≈ -CD>H2O, in contrast to the binding constant values and the structure
of these complexes. The effect of these cyclodextrins on the quenching process is discussed on the basis of the parameters obtained by fitting the
experimental data to the modified Stern–Volmer, and finite-sink approximation models.
2026-04-17T10:43:44Z
2026-04-17T10:43:44Z
2006-11-15
info:eu-repo/semantics/article
Valero, López-Cornejo, & Costa. (2007). Effect of the structure and concentration of cyclodextrins in the quenching process of naproxen. Journal of Photochemistry and Photobiology A: Chemistry, 188(1), 5-11. https://doi.org/10.1016/J.JPHOTOCHEM.2006.11.011
1010-6030
http://hdl.handle.net/10366/171024
10.1016/J.JPHOTOCHEM.2006.11.011
eng
https://doi.org/10.1016/J.JPHOTOCHEM.2006.11.011
http://creativecommons.org/licenses/by-nc-nd/4.0/
info:eu-repo/semantics/openAccess
Attribution-NonCommercial-NoDerivatives 4.0 Internacional
Elsevier