<?xml version="1.0" encoding="UTF-8"?><?xml-stylesheet type="text/xsl" href="static/style.xsl"?><OAI-PMH xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/ http://www.openarchives.org/OAI/2.0/OAI-PMH.xsd"><responseDate>2026-09-07T02:20:47Z</responseDate><request verb="GetRecord" identifier="oai:gredos.usal.es:10366/83203" metadataPrefix="dim">https://gredos.usal.es/oai/request</request><GetRecord><record><header><identifier>oai:gredos.usal.es:10366/83203</identifier><datestamp>2025-06-05T12:40:28Z</datestamp><setSpec>com_10366_4019</setSpec><setSpec>com_10366_3947</setSpec><setSpec>com_10366_3946</setSpec><setSpec>com_10366_3823</setSpec><setSpec>com_10366_4756</setSpec><setSpec>com_10366_4746</setSpec><setSpec>col_10366_4027</setSpec><setSpec>col_10366_68517</setSpec></header><metadata><dim:dim xmlns:dim="http://www.dspace.org/xmlns/dspace/dim" xmlns:doc="http://www.lyncode.com/xoai" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.dspace.org/xmlns/dspace/dim http://www.dspace.org/schema/dim.xsd">
<dim:field mdschema="dc" element="contributor" qualifier="advisor" authority="b6fd9dfb-1fef-4266-b8a3-30ec7b8e2c1f" confidence="500" orcid_id="">Cañizo Fernández-Roldán, María Consuelo del</dim:field>
<dim:field mdschema="dc" element="contributor" qualifier="advisor" authority="2422" confidence="500" orcid_id="">Sánchez-Guijo Martín, Fermín</dim:field>
<dim:field mdschema="dc" element="contributor" qualifier="advisor" authority="4d962d3c-ed6d-4191-9940-0c4d8680eea3" confidence="500" orcid_id="">López Holgado, Natalia</dim:field>
<dim:field mdschema="dc" element="contributor" qualifier="author" authority="8767fff5-c423-440f-be80-718921c8f2f9" confidence="500" orcid_id="">Carrancio Antón, Soraya</dim:field>
<dim:field mdschema="dc" element="date" qualifier="accessioned">2011-04-06T08:59:23Z</dim:field>
<dim:field mdschema="dc" element="date" qualifier="available">2011-04-06T08:59:23Z</dim:field>
<dim:field mdschema="dc" element="date" qualifier="issued">2010-12-17</dim:field>
<dim:field mdschema="dc" element="identifier" qualifier="uri">http://hdl.handle.net/10366/83203</dim:field>
<dim:field mdschema="dc" element="identifier" qualifier="doi">10.14201/gredos.83203</dim:field>
<dim:field mdschema="dc" element="description" qualifier="abstract">[EN] The hematopoietic stem cell transplantation (HSCT) is a therapeutic procedure designed to reconstitute the hematopoietic tissue of the patient, usually presents a bone marrow failure or have a neoplastic disease. Since the late nineteenth century, Brown-Sequard raised the possibility of reconstituting the production of blood cells in cases of anemia with the administration of spleen of animals, raw or cooked. It was not until the 50's when it got to reconstitute hematopoiesis in mice subjected to a lethal dose of irradiation, by intravenous administration of hematopoietic cells from another mouse, confirming the real possibility of organ transplant.</dim:field>
<dim:field mdschema="dc" element="description" qualifier="abstract" lang="es_ES">[ES] El trasplante de progenitores hematopoyéticos (TPH) es un procedimiento&#xd;
terapéutico destinado a reconstituir el tejido hematopoyético del paciente, que&#xd;
generalmente presenta una insuficiencia medular o sufre una enfermedad neoplásica. Ya a finales del S.XIX, Brown-Sequard planteó la posibilidad de reconstituir&#xd;
la producción de células sanguíneas en casos de anemia con la administración de&#xd;
bazo de animales, crudo o cocido. Pero no fue hasta los años 50 cuando se consiguió&#xd;
reconstituir la hematopoyesis en ratones sometidos a una dosis letal de irradiación,&#xd;
mediante la administración intravenosa de células hematopoyéticas de otro ratón,&#xd;
confirmando así la posibilidad real de un trasplante hematopoyético.</dim:field>
<dim:field mdschema="dc" element="format" qualifier="extent">160 p.</dim:field>
<dim:field mdschema="dc" element="format" qualifier="mimetype">application/pdf</dim:field>
<dim:field mdschema="dc" element="language">Español</dim:field>
<dim:field mdschema="dc" element="language" qualifier="iso" lang="es_ES">spa</dim:field>
<dim:field mdschema="dc" element="publisher" lang="es_ES">Universidad de Salamanca (España)</dim:field>
<dim:field mdschema="dc" element="rights">Attribution-NonCommercial-NoDerivs 3.0 Unported</dim:field>
<dim:field mdschema="dc" element="rights" qualifier="uri">https://creativecommons.org/licenses/by-nc-nd/3.0/</dim:field>
<dim:field mdschema="dc" element="rights" qualifier="accessRights">info:eu-repo/semantics/openAccess</dim:field>
<dim:field mdschema="dc" element="subject" lang="es_ES">Tesis y disertaciones académicas</dim:field>
<dim:field mdschema="dc" element="subject" lang="es_ES">Universidad de Salamanca (España)</dim:field>
<dim:field mdschema="dc" element="subject" lang="es_ES">Academic dissertations</dim:field>
<dim:field mdschema="dc" element="subject" lang="es_ES">Células mesenquimales</dim:field>
<dim:field mdschema="dc" element="subject" lang="es_ES">In vitro</dim:field>
<dim:field mdschema="dc" element="subject" lang="es_ES">Injertos</dim:field>
<dim:field mdschema="dc" element="subject" lang="es_ES">Transplantes hematopoyéticos</dim:field>
<dim:field mdschema="dc" element="subject" lang="es_ES">Mesenchymal stem cells</dim:field>
<dim:field mdschema="dc" element="subject" lang="es_ES">Implants</dim:field>
<dim:field mdschema="dc" element="subject" qualifier="unesco" lang="es_ES">3213.14 Cirugía de Los Trasplantes</dim:field>
<dim:field mdschema="dc" element="title" lang="es_ES">Papel de las células mesenquimales expandidas in vitro para mejorar el injerto en el contexto del trasplante hematopoyético</dim:field>
<dim:field mdschema="dc" element="type" lang="es_ES">info:eu-repo/semantics/doctoralThesis</dim:field>
<dim:field mdschema="dc" element="type" lang="es_ES">info:eu-repo/semantics/doctoralThesis</dim:field>
</dim:dim></metadata></record></GetRecord></OAI-PMH>