TY  - JOUR 
AU  - Montaño, Adrián
AU  - Ordóñez García, José Luis
AU  - Alonso-Pérez, Verónica
AU  - Hernández Sánchez, Jesús María
AU  - Santos, Sandra
AU  - González, Teresa
AU  - Benito Sánchez, Rocío
AU  - García-Tuñón, Ignacio
AU  - Hernández Rivas, Jesús María
PY  - 2020
UR  - http://hdl.handle.net/10366/147480
AB  - [EN]Background: The t(12;21)(p13;q22), which fuses ETV6 and RUNX1 genes, is the most common genetic abnormality in children with B-cell precursor acute lymphoblastic leukaemia. The implication of the fusion protein in leukemogenesis seems to be clear....
LA  - eng
PB  - MDPI
KW  - Acute lymphoblastic leukemia
KW  - ETV6/RUNX1
KW  - CRISP/Cas9
KW  - Genome edition
KW  - CRISPR-Cas Systems
KW  - Leukemia, Lymphoid
KW  - Genome
TI  - ETV6/RUNX1 Fusion Gene Abrogation Decreases the Oncogenicity of Tumour Cells in a Preclinical Model of Acute Lymphoblastic Leukaemia
DO  - 10.3390/cells9010215
T2  - Cells
VL  - 9
M2  - 215
ER  -