TY  - JOUR 
AU  - Álvarez Lozano, Raquel
AU  - Aramburu Villar, Laura
AU  - Gajate, Consuelo
AU  - Vicente Blázquez, Alba
AU  - Mollinedo García, Faustino
AU  - Medarde Agustín, Manuel
AU  - Peláez Lamamie de C. Arroyo, Rafael
PY  - 2021
SN  - 0223-5234
UR  - http://hdl.handle.net/10366/148385
AB  - The microtubules of the eukaryotic cells are hollow dynamic tubes formed by polymerization and depolymerization of αβ-tubulin heterodimers, referred to as tubulin. This dynamic equilibrium is essential for their functioning and the aim of...
LA  - eng
KW  - Isocombretastatins and phenstatin oximes
KW  - Pyridine analogs
KW  - Solubility improvement
KW  - Tubulin polymerization inhibition
KW  - G2/M arrest and apoptosis
KW  - Docking
TI  - Methylsulfanylpyridine based diheteroaryl isocombretastatin analogs as potent anti-proliferative agents
DO  - 10.1016/j.ejmech.2020.112933
T2  - European Journal of Medicinal Chemistry
VL  - 209
M2  - 112933
ER  -