TY - JOUR AU - Mateos Manteca, María Victoria AU - Oriol, Albert AU - Martinez-Lopez, Joaquin AU - Gutiérrez Gutiérrez, Norma Carmen AU - Teruel, Ana-Isabel AU - de Paz, Raquel AU - García-Laraña, José AU - Bengoechea, Enrique AU - Martin, Alejandro AU - Díaz-Mediavilla, Joaquín AU - Palomera, Luis AU - De Arriba, Felipe AU - González, Yolanda AU - Hernández, José-Mariano AU - Sureda, Anna AU - Bello, José-Luis AU - Bargay, Joan AU - Peñalver, Francisco-Javier AU - Ribera, José-María AU - Martín-Mateos, María-Luisa AU - García Sanz, Ramón AU - Cibeira, María-Teresa AU - Martín-Ramos, María-Luisa AU - Vidriales Vicente, María Belén AU - Paiva, Bruno AU - Montalbán, María-Angeles AU - Lahuerta, Juan José AU - Bladé, Joan AU - San Miguel Izquierdo, Jesús Fernando PY - 2010 UR - http://hdl.handle.net/10366/154347 AB - [EN]Bortezomib plus melphalan and prednisone (VMP) is significantly better than melphalan plus prednisone alone for elderly patients with untreated multiple myeloma; however, toxic effects are high. We investigated a novel and less intensive... LA - eng PB - Elsevier KW - Mieloma múltiple KW - Aged KW - Boronic Acids KW - Kaplan-Meier Estimate KW - Risk Assessment KW - Drug Administration Schedule KW - Humans KW - Pyrazines KW - Melphalan KW - Angiogenesis Inhibitors KW - Antineoplastic Combined Chemotherapy Protocols KW - Antineoplastic Agents KW - Multiple Myeloma KW - Time Factors KW - Risk Factors KW - Proportional Hazards Models KW - Thalidomide KW - Treatment Outcome KW - Protease Inhibitors KW - Prednisone TI - Bortezomib, melphalan, and prednisone versus bortezomib, thalidomide, and prednisone as induction therapy followed by maintenance treatment with bortezomib and thalidomide versus bortezomib and prednisone in elderly patients with untreated multiple myeloma: a randomised trial DO - 10.1016/S1470-2045(10)70187-X T2 - The Lancet. Oncology VL - 11 M2 - 934 ER -