TY  - JOUR 
AU  - Mackintosh Ginel, Carlos Jesús
AU  - García Domínguez, Daniel José
AU  - Ordóñez García, José Luis
AU  - Ginel Picardo, Alicia
AU  - Smith, P. G.
AU  - Sacristán Martín, María Paz
AU  - de Álava Casado, Enrique
PY  - 2013
UR  - http://hdl.handle.net/10366/154357
AB  - [EN]Ewing sarcoma (ES) is an aggressive bone and soft tissue tumor of children and young adults in which finding effective new
targeted therapies is imperative. Here, we report an in-depth preclinical study of the investigational cullin-RING...
LA  - eng
PB  - Springer Nature
KW  - WEE1
KW  - Cyclin A
KW  - Cyclin E
KW  - P27
KW  - MLN4924
KW  - Ewing sarcoma
KW  - Sarcoma, Ewing
TI  - WEE1 accumulation and deregulation of S-phase proteins mediate MLN4924 potent inhibitory effect on Ewing sarcoma cells
DO  - 10.1038/ONC.2012.153
T2  - Oncogene
VL  - 32
M2  - 1441
ER  -