TY - JOUR AU - Pedicona, Federico AU - Casado, Pedro AU - Hijazi Vega, Maruan AU - Gribben, John G. AU - Rouault-Pierre, Kevin AU - Cutillas, Pedro R PY - 2022 SN - 1945-0877 UR - http://hdl.handle.net/10366/154472 AB - Most tumor types either fail to respond or become resistant to kinase inhibitors, often because of compensatory prosurvival pathways in the cancer cell's broader signaling circuitry. Here, we found that intrinsic resistance to kinase inhibitors in... LA - eng KW - Antineoplastic Agents KW - Protein Kinase Inhibitors KW - Histone Demethylases KW - KDM1A protein, human KW - Mitogen-Activated Protein Kinase Kinases KW - Lysine TI - Targeting the lysine-specific demethylase 1 rewires kinase networks and primes leukemia cells for kinase inhibitor treatment DO - 10.1126/scisignal.abl7989 T2 - Science Signaling VL - 15 ER -