TY  - JOUR 
AU  - Amaral, Ana Teresa
AU  - Garofalo, Cecilia
AU  - Frapolli, Roberta
AU  - Manara, María Cristina
AU  - Mancarella, Caterina
AU  - Uboldi, Sarah
AU  - Giandomenico, Silvana Di
AU  - Ordóñez García, José Luis
AU  - Sevillano, María Victoria
AU  - Malaguarnera, Roberta
AU  - Picci, Piero
AU  - Hassan, A. Bass
AU  - de Álava Casado, Enrique
AU  - D'Incalci, Maurizio
AU  - Scotlandi, Katia
PY  - 2015
SN  - 1078-0432
UR  - http://hdl.handle.net/10366/154480
AB  - [EN]Purpose: Goal of this study was to identify mechanisms that limit efficacy of trabectedin (ET-743, Yondelis) in Ewing sarcoma (EWS), so as to develop a clinical applicable combination therapy. Experimental Design: By chromatin immunoprecipitation,...
LA  - eng
PB  - American Association for Cancer Research
KW  - IGF1R
KW  - Trabectedin
KW  - Ewing sarcoma
KW  - Sarcoma de Ewing
KW  - Sarcoma, Ewing
TI  - Trabectedin efficacy in Ewing sarcoma Is greatly increased by combination with anti-IGF signaling agents
DO  - 10.1158/1078-0432.CCR-14-1688
T2  - Clinical Cancer Research
VL  - 21
M2  - 1373
ER  -