TY - JOUR AU - Paíno Gómez, María Teresa AU - Gangoso Rodríguez, Ester AU - Medina Jiménez, José María AU - Tabernero Urbieta, María Aránzazu PY - 2010 SN - 0028-3908 UR - http://hdl.handle.net/10366/154807 AB - [EN]It is well known that the efficiency of Herpes simplex virus thymidine kinase gene/ganciclovir (HSV-tk/GCV) therapy is improved by the bystander effect, which mainly relies on gap junctional intercellular communication (GJIC). Malignant gliomas... LA - eng PB - Elsevier KW - Glioma KW - Bystander effect KW - HSV-tk/GCV KW - In Situ Nick-End Labeling KW - Reverse Transcriptase Polymerase Chain Reaction KW - Analysis of Variance KW - Transfection KW - Flow Cytometry KW - Humans KW - Cells KW - Bystander Effect KW - Cell Line KW - KATP Channels KW - RNA KW - Thymidine Kinase KW - Gap Junctions KW - Simplexvirus KW - Viral Proteins KW - Ganciclovir TI - Inhibition of ATP-sensitive potassium channels increases HSV-tk/GCV bystander effect in U373 human glioma cells by enhancing gap junctional intercellular communication DO - 10.1016/j.neuropharm.2010.06.011 T2 - Neuropharmacology VL - 59 M2 - 480 ER -