TY - JOUR AU - Pérez Fernández, Alejandro AU - López Ruano, Guillermo AU - Prieto Bermejo, Rodrigo AU - Ijurko Valeta, Carla AU - Díez-Campelo, María AU - Sánchez Guijo Martín, Fermín AU - Hernández Hernández, Ángel PY - 2019 UR - http://hdl.handle.net/10366/155172 AB - [EN]The differentiation-based therapy for acute promyelocytic leukemia (APL) is an inspiring example for the search of novel strategies aimed at treatment of other subtypes of acute myeloid leukemia (AML). Thus, the discovery of new molecular players... LA - eng PB - BMC KW - SHP1 KW - SHP2 KW - Cell differentiation KW - Phorbol esters KW - Acute myeloid leukemia KW - Pro-differentiating therapy KW - Leukemia KW - Phorbol Esters KW - Animals KW - Xenograft Model Antitumor Assays KW - Cell Differentiation KW - Humans KW - Mice TI - SHP1 and SHP2 inhibition enhances the pro-differentiative effect of phorbol esters: an alternative approach against acute myeloid leukemia DO - 10.1186/s13046-019-1097-z T2 - Journal of Experimental and Clinical Cancer Research VL - 38 M2 - 14 ER -