TY - JOUR AU - Valbuena-Diez, Ana C AU - Blanco, Francisco J. AU - Oujo, Barbara AU - Langa, Carmen AU - González Núñez, María AU - Llano Cuadra, María Elena AU - Pendás, Alberto M. AU - Díaz, Mercedes AU - Castrillo, Antonio AU - López-Novoa, José M. AU - Bernabeu, Carmelo PY - 2012 SN - 0009-7322 UR - http://hdl.handle.net/10366/155182 AB - [EN]Ischemia in the placenta is considered the base of the pathogenesis of preeclampsia, a pregnancy-specific syndrome in which soluble endoglin (sEng) is a prognostic marker and plays a pathogenic role. Here, we investigated the effects of hypoxia... LA - eng PB - Lippincott Williams & Wilkins KW - Cell hypoxia KW - Hypertension KW - Pre-eclampsia KW - Pregnancy KW - Peptides KW - Antigens KW - Anticholesteremic Agents KW - Hydrocarbons KW - Choriocarcinoma KW - Hydroxycholesterols KW - Orphan Nuclear Receptors KW - Humans KW - Cell Line KW - Ischemia KW - Blood Pressure KW - Pre-Eclampsia KW - Pregnancy KW - Sulfonamides KW - Human Umbilical Vein Endothelial Cells KW - Intracellular Signaling Peptides and Proteins KW - Tissue Inhibitor of Metalloproteinase-3 KW - Placenta Diseases KW - Animals KW - Matrix Metalloproteinase 14 KW - Uterine Neoplasms KW - Mice TI - Oxysterol-induced soluble endoglin release and its involvement in hypertension DO - 10.1161/CIRCULATIONAHA.112.101261 T2 - Circulation VL - 126 M2 - 2612 ER -