TY - JOUR AU - Alonso Sarasquete, María Eugenia AU - García Sanz, Ramón AU - Marín Rubio, Luis Alberto AU - Alcoceba Sánchez, Miguel AU - Chillón Santos, María del Carmen AU - Balanzategui, A AU - Santamaria, Carlos AU - Rosiñol, Laura AU - De la Rubia, Javier AU - Hernandez, Miguel T. AU - Garcia-Navarro, Inmaculada AU - Lahuerta, Juan José AU - González Díaz, Marcos AU - San Miguel Izquierdo, Jesús Fernando PY - 2008 SN - 0006-4971 UR - http://hdl.handle.net/10366/155234 AB - [EN]We have explored the potential role of genetics in the development of osteonecrosis of the jaw (ONJ) in multiple myeloma (MM) patients under bisphosphonate therapy. A genome-wide association study was performed using 500 568 single nucleotide... LA - eng PB - American Society of Hematology KW - Bisphosphonate KW - Osteonecrosis of the Jaw KW - Myeloma KW - Genetic Polymorphisms KW - Genetic Predisposition to Disease KW - Diphosphonates KW - Jaw Diseases KW - Multiple Myeloma KW - Alleles KW - Haplotypes KW - Humans KW - Genome KW - Osteonecrosis KW - Aryl Hydrocarbon Hydroxylases TI - Bisphosphonate-related osteonecrosis of the jaw is associated with polymorphisms of the cytochrome P450 CYP2C8 in multiple myeloma: a genome-wide single nucleotide polymorphism analysis DO - 10.1182/blood-2008-04-147884 T2 - Blood VL - 112 M2 - 2709 ER -