TY - JOUR AU - Cobaleda, C. AU - Gutiérrez-Cianca, N. AU - Pérez Losada, Jesús AU - Flores, T. AU - García Sanz, Ramón AU - González Díaz, Marcos AU - Sánchez Garcı́a, Isidro PY - 2000 SN - 0006-4971 UR - http://hdl.handle.net/10366/155236 AB - [EN]BCR-ABL is a chimeric oncogene generated by translocation of sequences from the chromosomal counterpart (c-ABL gene) on chromosome 9 into the BCR gene on chromosome 22. Alternative chimeric proteins, BCR-ABL(p190) and BCR-ABL(p210), are produced... LA - eng PB - American Society of Hematology KW - Lymphoblastic leukemia KW - Stem cell KW - Philadelphia chromosome KW - Cell division KW - Antigens KW - Immunophenotyping KW - Cell Differentiation KW - Humans KW - Cell Division KW - Hematopoietic Stem Cells KW - Neoplasm Transplantation KW - Membrane Glycoproteins KW - NAD+ Nucleosidase KW - Philadelphia Chromosome KW - Precursor Cell Lymphoblastic Leukemia-Lymphoma KW - Animals KW - ADP-ribosyl Cyclase KW - Neoplastic Stem Cells KW - Mice TI - A primitive hematopoietic cell is the target for the leukemic transformation in human philadelphia-positive acute lymphoblastic leukemia DO - 10.1182/blood.V95.3.1007.003k35_1007_1013 T2 - Blood VL - 95 M2 - 1007 ER -