TY  - JOUR 
AU  - Barrio, Emilia
AU  - Vecino Pérez, Rebeca
AU  - Sánchez Morán, Irene
AU  - Rodríguez González, Cristina
AU  - Suárez Pindado, Alberto
AU  - Bolaños Hernández, Juan Pedro
AU  - Almeida Parra, María Ángeles
AU  - Delgado Esteban, María
PY  - 2021
SN  - 1661-6596
UR  - http://hdl.handle.net/10366/155253
AB  - EN][One of the most important mechanisms of preconditioning-mediated neuroprotection is the attenuation of cell apoptosis, inducing brain tolerance after a subsequent injurious ischemia. In this context, the antiapoptotic PI3K/AKT signaling pathway...
LA  - eng
PB  - MDPI
KW  - AKT
KW  - MDM2
KW  - p53
KW  - PI3K
KW  - Ischemic tolerance
KW  - Preconditioning
KW  - Proto-Oncogene Proteins c-mdm2
KW  - Ischemic Preconditioning
KW  - HEK293 Cells
KW  - Humans
KW  - Ischemia
KW  - Neurons
KW  - Apoptosis
KW  - Phosphorylation
KW  - Animals
KW  - Proto-Oncogene Proteins c-akt
KW  - Tumor Suppressor Protein p53
KW  - Signal Transduction
KW  - Phosphatidylinositol 3-Kinases
KW  - Mice
TI  - Preconditioning-activated AKT controls neuronal tolerance to ischemia through the MDM2-p53 pathway
DO  - 10.3390/ijms22147275
T2  - International Journal of Molecular Science
VL  - 22
M2  - 7275
ER  -