TY  - JOUR 
AU  - Rodríguez González, Cristina
AU  - Ramos Araque, María Esther
AU  - Domínguez-Martínez, Marta
AU  - Sobrino, Tomás
AU  - Sánchez Morán, Irene
AU  - Agulla Freire, Jesús
AU  - Delgado Esteban, María
AU  - Gómez Sánchez, José Carlos
AU  - Bolaños Hernández, Juan Pedro
AU  - Castillo, José
AU  - Almeida Parra, María Ángeles
PY  - 2018
SN  - 0039-2499
UR  - http://hdl.handle.net/10366/155254
AB  - [EN]Background and Purpose- The E3 ubiquitin ligase MDM2 (murine double minute 2) is the main negative regulator of the p53 protein-a key player in neuronal apoptosis after ischemia. A functional single-nucleotide polymorphism in the human MDM2 gene...
LA  - eng
PB  - Lippincott, Williams & Wilkins
KW  - Alleles
KW  - Apoptosis
KW  - Brain ischemia
KW  - Cerebral hemorrhage
KW  - Prognosis
KW  - Stroke
KW  - Proto-Oncogene Proteins c-mdm2
KW  - Genetic Predisposition to Disease
KW  - Genotype
KW  - Risk Factors
KW  - Alleles
KW  - Animals
KW  - Humans
KW  - Recovery of Function
KW  - Stroke
KW  - Mice
TI  - Single-nucleotide polymorphism 309T>G in the MDM2 promoter determines functional outcome after stroke
DO  - 10.1161/STROKEAHA.118.022529
T2  - Stroke
VL  - 49
M2  - 2437
ER  -