TY - JOUR AU - Dimopoulos, Meletios A. AU - Tedeschi, Alessandra AU - Trotman, Judith AU - García Sanz, Ramón AU - Macdonald, David AU - Leblond, Veronique AU - Mahe, Beatrice AU - Herbaux, Charles AU - Tam, Constantine AU - Orsucci, Lorella AU - Palomba, M. Lia AU - Matous, Jeffrey V. AU - Shustik, Chaim AU - Kastritis, Efstathios AU - Treon, Steven P. AU - Li, J. AU - Salman, Zeena AU - Graef, Thorsten AU - Buske, Christian PY - 2018 SN - 0028-4793 UR - http://hdl.handle.net/10366/155425 AB - [EN]Single-agent ibrutinib has shown substantial activity in patients with relapsed Waldenström's macroglobulinemia, a rare form of B-cell lymphoma. We evaluated the effect of adding ibrutinib to rituximab in patients with this disease, both in those... LA - eng PB - NEJM Group KW - Waldenstrom macroglobulinemia KW - Ibrutinib KW - Rituximab KW - Randomized trial KW - Disease-Free Survival KW - Adenine KW - Aged KW - Adult KW - Humans KW - Antineoplastic Combined Chemotherapy Protocols KW - Middle Aged KW - Hemoglobins KW - Waldenstrom Macroglobulinemia KW - Pyrazoles KW - Pyrimidines KW - Atrial Fibrillation KW - Immunoglobulin M KW - Survival Analysis KW - Piperidines TI - Phase 3 trial of ibrutinib plus rituximab in Waldenström's macroglobulinemia DO - 10.1056/NEJMoa1802917 T2 - New England Journal of Medicine VL - 378 M2 - 2399 ER -