TY - JOUR AU - Jimeno García, David AU - Lillo Delgado, María Concepción AU - de la Villa, Pedro AU - Calzada, Nuria AU - Santos de Dios, Eugenio Miguel AU - Fernández Medarde, Alberto PY - 2023 UR - http://hdl.handle.net/10366/156403 AB - [ES]Utilizando ratones knockout para GRF1/2 constitutivos, demostramos previamente que GRF2 es un regulador clave de la migración nuclear en los fotorreceptores de los conos de la retina. Para evaluar la relevancia funcional de ese proceso celular... AB - [EN]Using constitutive GRF1/2 knockout mice, we showed previously that GRF2 is a key regulator of nuclear migration in retinal cone photoreceptors. To evaluate the functional relevance of that cellular process for two putative targets of the GEF... LA - eng PB - MDPI KW - Cone photoreceptor KW - GRF2 KW - CDC42 KW - RAC KW - Nuclear movement KW - Cell death KW - Ribbon synapsis KW - Retina KW - Degeneration TI - GRF2 Is crucial for cone photoreceptor viability and ribbon synapse formation in the mouse retina DO - 10.3390/cells12212574 T2 - Cells VL - 12 M2 - 2574 ER -