TY - JOUR AU - Hernández, Luis AU - Beà, Sílvia AU - Bellosillo, Beatriz AU - Pinyol, Magda AU - Falini, Brunangelo AU - Carbone, Antonino AU - Ott, German AU - Rosenwald, Andreas AU - Fernández Medarde, Alberto AU - Pulford, Karen AU - Mason, David AU - Morris, Stephan W. AU - Santos de Dios, Eugenio Miguel AU - Campo, Elias PY - 2002 SN - 0002-9440 UR - http://hdl.handle.net/10366/156660 AB - [ES]En este artículo describimos una nueva serie de traslocaciones cromosómicas causanes del linfoma anaplásico de célula grande. En estas traslocaciones, TFG puede utilizar una variedad de puntos de ruptura intrónicos en reordenamientos de ALK que... AB - [EN]Anaplastic large cell lymphomas are associated with chromosomal aberrations involving the anaplastic lymphoma kinase (ALK) gene at 2p23 that result in the expression of novel chimeric ALK proteins with transforming properties. In most of these... LA - eng PB - Elsevier KW - TFG-ALK KW - Anaplastic large cell lymphomas KW - Traslocation KW - Transformation KW - Signaling KW - Genomic breakpoints KW - Lymphoma, Large-Cell, Anaplastic TI - Diversity of genomic breakpoints in TFG-ALK translocations in anaplastic large cell lymphomas : Identification of a new TFG-ALKXL chimeric gene with transforming activity DO - 10.1016/S0002-9440(10)62574-6 T2 - The American Journal of Pathology VL - 160 M2 - 1487 ER -