TY - JOUR AU - López, S N AU - Castelli, M V AU - Zacchino, S A AU - Domínguez, J N AU - Lobo, G AU - Charris-Charris, J AU - García Cortés, Juan Carlos AU - Ribas Elcorobarrutia, Juan Carlos AU - Devia, C AU - Rodríguez, A M AU - Enriz, R D AU - López, Silvia N AU - Castelli, Marı́a V AU - Zacchino, Susana A AU - Domı́nguez, José N AU - Lobo, Gricela AU - Charris-Charris, Jaime AU - Cortés, Juan C.G AU - Ribas, Juan C AU - Devia, Cristina AU - Rodrı́guez, Ana M AU - Enriz, Ricardo D PY - 2001 SN - 0968-0896 UR - http://hdl.handle.net/10366/157235 AB - [EN]Here we report the synthesis, in vitro antifungal evaluation and SAR study of 41 chalcones and analogues. In addition, all active structures were tested for their capacity of inhibiting Saccharomyces cerevisiae beta(1,3)-glucan synthase and chitin... LA - eng PB - Elsevier KW - Antifungal Agents KW - Microbial Sensitivity Tests KW - Structure-Activity Relationship KW - Saccharomyces cerevisiae KW - Molecular Conformation KW - Polymers KW - Antifungal Agents KW - Polymers KW - Structure-Activity Relationship KW - Microbial Sensitivity Tests KW - Molecular Conformation KW - Chalcone KW - Cell Wall KW - Saccharomyces cerevisiae KW - Evaluation Studies as Topic TI - In vitro antifungal evaluation and structure-activity relationships of a new series of chalcone derivatives and synthetic analogues, with inhibitory properties against polymers of the fungal cell wall. DO - 10.1016/S0968-0896(01)00116-X T2 - Bioorganic and Medicinal Chemistry VL - 9 M2 - 1999 ER -