TY - JOUR AU - Pedicona, Federico AU - Casado, Pedro AU - Hijazi Vega, Maruan AU - Gribben, John G AU - Rouault-Pierre, Kevin AU - Cutillas, Pedro R PY - 2022 UR - http://hdl.handle.net/10366/161299 AB - [EN]Most tumor types either fail to respond or become resistant to kinase inhibitors, often because of compensatory prosurvival pathways in the cancer cell's broader signaling circuitry. Here, we found that intrinsic resistance to kinase inhibitors in... LA - eng PB - American Association for the Advancement of Science KW - Antineoplastic Agents KW - Leukemia Myeloid Acute KW - Histone Demethylases KW - Lysine KW - Mitogen Activated Protein Kinase Kinases KW - Protein Kinase Inhibitors KW - Mitogen-Activated Protein Kinase Kinases KW - Histone Demethylases KW - Leukemia KW - Humans KW - Lysine KW - Cell Line KW - Antineoplastic Agents KW - Protein Kinase Inhibitors TI - Targeting the lysine-specific demethylase 1 rewires kinase networks and primes leukemia cells for kinase inhibitor treatment. DO - 10.1126/scisignal.abl7989 T2 - Science Signaling VL - 15 M2 - eabl7989 ER -